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- Q18387473 subject Q22902012.
- Q18387473 subject Q7215865.
- Q18387473 subject Q8852199.
- Q18387473 abstract "Penicilloic acid is any of several acids which are obtained from the penicillins by the hydrolytic opening of the lactam ring (as by the action of a beta-lactamase).Hypersensitivity is the most important adverse effect of the penicillins. The major antigenic determinant of penicillin hypersensitivity is its metabolite, penicilloic acid, which reacts with proteins and serves as a hapten to cause an immune reaction. Approximately five percent of patients have some kind of reaction, ranging from maculopapular rash (the most common rash seen with ampicillin hypersensitivity) to angioedema (marked swelling of the lips, tongue, and periorbital area) and anaphylaxis. Among patients with mononucleosis who are treated with ampicillin, the incidence of maculopapular rash approaches 100 percent. Cross-allergic reactions occur among the β-lactam antibiotics. To determine whether treatment with a β-lactam is safe when an allergy is noted, patient history regarding severity of previous reaction is essential.".
- Q18387473 iupacName "(2R,4S)-2-[(R)-Carboxy(formamido)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid".
- Q18387473 thumbnail Penicilloic_acid.png?width=300.
- Q18387473 wikiPageWikiLink Q103135.
- Q18387473 wikiPageWikiLink Q103537.
- Q18387473 wikiPageWikiLink Q1059.
- Q18387473 wikiPageWikiLink Q1129007.
- Q18387473 wikiPageWikiLink Q12190.
- Q18387473 wikiPageWikiLink Q168800.
- Q18387473 wikiPageWikiLink Q2071037.
- Q18387473 wikiPageWikiLink Q207367.
- Q18387473 wikiPageWikiLink Q22902012.
- Q18387473 wikiPageWikiLink Q244150.
- Q18387473 wikiPageWikiLink Q251124.
- Q18387473 wikiPageWikiLink Q306264.
- Q18387473 wikiPageWikiLink Q311379.
- Q18387473 wikiPageWikiLink Q407595.
- Q18387473 wikiPageWikiLink Q42982.
- Q18387473 wikiPageWikiLink Q506441.
- Q18387473 wikiPageWikiLink Q5958765.
- Q18387473 wikiPageWikiLink Q6725808.
- Q18387473 wikiPageWikiLink Q7215865.
- Q18387473 wikiPageWikiLink Q8852199.
- Q18387473 iupacname "-2".
- Q18387473 type ChemicalCompound.
- Q18387473 type ChemicalSubstance.
- Q18387473 type ChemicalObject.
- Q18387473 type Thing.
- Q18387473 type Q11173.
- Q18387473 comment "Penicilloic acid is any of several acids which are obtained from the penicillins by the hydrolytic opening of the lactam ring (as by the action of a beta-lactamase).Hypersensitivity is the most important adverse effect of the penicillins. The major antigenic determinant of penicillin hypersensitivity is its metabolite, penicilloic acid, which reacts with proteins and serves as a hapten to cause an immune reaction.".
- Q18387473 label "Penicilloic acid".
- Q18387473 depiction Penicilloic_acid.png.