Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q18043056> ?p ?o }
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- Q18043056 subject Q8760327.
- Q18043056 abstract "Potassium-chloride transporter member 5 (aka: KCC2 and SLC12A5) is a neuron-specific chloride potassium symporter responsible for establishing the chloride ion gradient in neurons through the maintenance of low intracellular chloride concentrations. It is a critical mediator of synaptic inhibition, cellular protection against excitotoxicity and may also act as a modulator of neuroplasticity. Potassium-chloride transporter member 5 is also known by the names: KCC2 (potassium chloride cotransporter 2) for its ionic substrates, and SLC12A5 for its genetic origin from the SLC12A5 gene in humans.Animals with reduced expression of this transporter exhibit severe motor deficits, epileptiform activity, and spasticity. KCC2 knockout animals, in which KCC2 is completely absent, die postnatally due to respiratory failure.".
- Q18043056 entrezgene "57468".
- Q18043056 wikiPageExternalLink 54540.php.
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- Q18043056 wikiPageWikiLink Q8760327.
- Q18043056 wikiPageWikiLink Q901117.
- Q18043056 type Biomolecule.
- Q18043056 type Protein.
- Q18043056 type Thing.
- Q18043056 type Q206229.
- Q18043056 type Q8054.
- Q18043056 comment "Potassium-chloride transporter member 5 (aka: KCC2 and SLC12A5) is a neuron-specific chloride potassium symporter responsible for establishing the chloride ion gradient in neurons through the maintenance of low intracellular chloride concentrations. It is a critical mediator of synaptic inhibition, cellular protection against excitotoxicity and may also act as a modulator of neuroplasticity.".
- Q18043056 label "Chloride potassium symporter 5".