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- Q18035892 abstract "Progesterone receptor membrane component 1 (abbreviated PGRMC1) is a protein which co-purifies with progesterone binding proteins in the liver and ovary. In humans, the PGRMC1 protein is encoded by the PGRMC1 gene. The Sigma-2 receptor was recently identified as potentially being the same as PGRMC1.The sole biochemical function of PGRMC1 is heme-binding. PGRMC1 shares key structural motifs with cytochrome b5. PGRMC1 binds and activates P450 proteins, which are important in drug, hormone and lipid metabolism. PGRMC1 also binds to PAIR-BP1 (plasminogen activator inhibitor RNA-binding protein-1). However, its expression outside of the reproductive tract and in males suggests multiple functions for the protein. These may include binding to Insig (insulin-induced gene), which regulates cholesterol synthesis.".
- Q18035892 entrezgene "10857".
- Q18035892 wikiPageWikiLink Q11087111.
- Q18035892 wikiPageWikiLink Q14358595.
- Q18035892 wikiPageWikiLink Q14864419.
- Q18035892 wikiPageWikiLink Q14907373.
- Q18035892 wikiPageWikiLink Q1543282.
- Q18035892 wikiPageWikiLink Q18038129.
- Q18035892 wikiPageWikiLink Q1805541.
- Q18035892 wikiPageWikiLink Q187661.
- Q18035892 wikiPageWikiLink Q189621.
- Q18035892 wikiPageWikiLink Q1931516.
- Q18035892 wikiPageWikiLink Q2236682.
- Q18035892 wikiPageWikiLink Q411114.
- Q18035892 wikiPageWikiLink Q423650.
- Q18035892 wikiPageWikiLink Q5169158.
- Q18035892 wikiPageWikiLink Q5201346.
- Q18035892 wikiPageWikiLink Q58321.
- Q18035892 wikiPageWikiLink Q7187.
- Q18035892 wikiPageWikiLink Q719725.
- Q18035892 wikiPageWikiLink Q749637.
- Q18035892 wikiPageWikiLink Q7512215.
- Q18035892 wikiPageWikiLink Q8054.
- Q18035892 type Biomolecule.
- Q18035892 type Protein.
- Q18035892 type Thing.
- Q18035892 type Q206229.
- Q18035892 type Q8054.
- Q18035892 comment "Progesterone receptor membrane component 1 (abbreviated PGRMC1) is a protein which co-purifies with progesterone binding proteins in the liver and ovary. In humans, the PGRMC1 protein is encoded by the PGRMC1 gene. The Sigma-2 receptor was recently identified as potentially being the same as PGRMC1.The sole biochemical function of PGRMC1 is heme-binding. PGRMC1 shares key structural motifs with cytochrome b5.".
- Q18035892 label "PGRMC1".