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- Q18033863 abstract "Autophagy-related protein 12 is a protein that in humans is encoded by the ATG12 gene.Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998).[supplied by OMIM]Autophagy requires the covalent attachment of the protein Atg12 to ATG5 through a ubiquitin-like conjugation system. The Atg12-Atg5 conjugate then promotes the conjugation of ATG8 to the lipid phosphatidylethanolamine.Atg12 was found to be involved in apoptosis. This protein promotes apoptosis through an interaction with anti-apoptotic members of the Bcl-2 family.".
- Q18033863 entrezgene "9140".
- Q18033863 wikiPageWikiLink Q14599311.
- Q18033863 wikiPageWikiLink Q18034312.
- Q18033863 wikiPageWikiLink Q288322.
- Q18033863 wikiPageWikiLink Q407111.
- Q18033863 wikiPageWikiLink Q426095.
- Q18033863 wikiPageWikiLink Q4654670.
- Q18033863 wikiPageWikiLink Q554446.
- Q18033863 wikiPageWikiLink Q7187.
- Q18033863 wikiPageWikiLink Q8054.
- Q18033863 type Biomolecule.
- Q18033863 type Protein.
- Q18033863 type Thing.
- Q18033863 type Q206229.
- Q18033863 type Q8054.
- Q18033863 comment "Autophagy-related protein 12 is a protein that in humans is encoded by the ATG12 gene.Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation.".
- Q18033863 label "ATG12".