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- Q18032928 abstract "Serum deprivation-response protein is a protein that in humans is encoded by the SDPR gene.This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein has also been shown to be a substrate for protein kinase C (PKC) phosphorylation.SDPR is shown to act as a metastasis suppressor by xenograft studies utilizing breast cancer cell lines.SDPR may elicit its metastasis suppressor function by directly interacting with ERK and limiting its pro-survival role. Moreover, it is suggested that SDPR is silenced during breast cancer progression by promoter DNA methylation. Metastasis suppressor role of SDPR may go beyond breast cancer since tumor samples from bladder, colorectal, lung, pancreatic, and ovarian cancers as well as sarcomas also exhibited loss of SDPR expression.".
- Q18032928 entrezgene "8436".
- Q18032928 wikiPageWikiLink Q110084.
- Q18032928 wikiPageWikiLink Q181876.
- Q18032928 wikiPageWikiLink Q186915.
- Q18032928 wikiPageWikiLink Q224093.
- Q18032928 wikiPageWikiLink Q26972.
- Q18032928 wikiPageWikiLink Q409325.
- Q18032928 wikiPageWikiLink Q420877.
- Q18032928 wikiPageWikiLink Q55505.
- Q18032928 wikiPageWikiLink Q7187.
- Q18032928 wikiPageWikiLink Q8054.
- Q18032928 wikiPageWikiLink Q874745.
- Q18032928 type Biomolecule.
- Q18032928 type Protein.
- Q18032928 type Thing.
- Q18032928 type Q206229.
- Q18032928 type Q8054.
- Q18032928 comment "Serum deprivation-response protein is a protein that in humans is encoded by the SDPR gene.This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells.".
- Q18032928 label "SDPR".