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- Q18028014 subject Q9016234.
- Q18028014 abstract "Integrin alpha-IIb is a protein that in humans is encoded by the ITGA2B gene.ITGA2B, also known as CD41, encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibrinogen receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.".
- Q18028014 entrezgene "3674".
- Q18028014 wikiPageWikiLink Q1103544.
- Q18028014 wikiPageWikiLink Q18021531.
- Q18028014 wikiPageWikiLink Q2335787.
- Q18028014 wikiPageWikiLink Q4654985.
- Q18028014 wikiPageWikiLink Q7187.
- Q18028014 wikiPageWikiLink Q8054.
- Q18028014 wikiPageWikiLink Q896177.
- Q18028014 wikiPageWikiLink Q9016234.
- Q18028014 type Biomolecule.
- Q18028014 type Protein.
- Q18028014 type Thing.
- Q18028014 type Q206229.
- Q18028014 type Q8054.
- Q18028014 comment "Integrin alpha-IIb is a protein that in humans is encoded by the ITGA2B gene.ITGA2B, also known as CD41, encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibrinogen receptor expressed in platelets that plays a crucial role in coagulation.".
- Q18028014 label "ITGA2B".