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- Q18027467 abstract "Isoleucyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the IARS gene.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.".
- Q18027467 entrezgene "3376".
- Q18027467 wikiPageWikiLink Q17916978.
- Q18027467 wikiPageWikiLink Q7187.
- Q18027467 wikiPageWikiLink Q8047.
- Q18027467 wikiPageWikiLink Q896177.
- Q18027467 type Biomolecule.
- Q18027467 type Protein.
- Q18027467 type Thing.
- Q18027467 type Q206229.
- Q18027467 type Q8054.
- Q18027467 comment "Isoleucyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the IARS gene.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution.".
- Q18027467 label "IARS".