Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q17913960> ?p ?o }
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- Q17913960 abstract "DNA fragmentation factor subunit beta is a protein that in humans is encoded by the DFFB gene.Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.".
- Q17913960 entrezgene "1677".
- Q17913960 symbol "DFF40".
- Q17913960 thumbnail PDB_1v0d_EBI.jpg?width=300.
- Q17913960 wikiPageWikiLink Q17913956.
- Q17913960 wikiPageWikiLink Q7187.
- Q17913960 wikiPageWikiLink Q8054.
- Q17913960 wikiPageWikiLink Q896177.
- Q17913960 symbol "DFF40".
- Q17913960 type Biomolecule.
- Q17913960 type Protein.
- Q17913960 type Thing.
- Q17913960 type Q206229.
- Q17913960 type Q8054.
- Q17913960 comment "DNA fragmentation factor subunit beta is a protein that in humans is encoded by the DFFB gene.Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits.".
- Q17913960 label "DFFB".
- Q17913960 depiction PDB_1v0d_EBI.jpg.