Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q176533> ?p ?o }
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- Q176533 subject Q6442932.
- Q176533 subject Q7029794.
- Q176533 subject Q7145146.
- Q176533 subject Q7334131.
- Q176533 subject Q7486806.
- Q176533 subject Q8253301.
- Q176533 subject Q8561887.
- Q176533 subject Q8645495.
- Q176533 subject Q8844648.
- Q176533 subject Q8971959.
- Q176533 subject Q9134654.
- Q176533 abstract "Alfentanil (R-39209, trade name Alfenta, Rapifen in Australia) is a potent but short-acting synthetic opioid analgesic drug, used for anaesthesia in surgery. It is an analogue of fentanyl with around 1/4 to 1/10 the potency of fentanyl and around 1/3 of the duration of action, but with an onset of effects 4x faster than fentanyl. Alfentanil has a pKa of approximately 6.5, which leads to a very high proportion of the drug being uncharged at physiologic pH. This unique characteristic is responsible for its rapid onset. It is an agonist at mu opioid receptors.While alfentanil tends to cause fewer cardiovascular complications than other similar drugs such as fentanyl and remifentanil, it tends to give stronger respiratory depression and so requires careful monitoring of breathing and vital signs. Almost exclusively used by anesthesia providers during portions of a case where quick, fast acting (though not long lasting) pain control is needed (i.e. during a nerve block, head pinning etc..) Alfentanil is administered by the parenteral (injected) route for fast onset of effects and precise control of dosage.Alfentanil is a restricted drug which is classified as Schedule II in the USA, according to the U.S. DEA website.Alfentanil was discovered at Janssen Pharmaceutica in 1976.Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear.".
- Q176533 atcPrefix "N01".
- Q176533 atcSuffix "AH02".
- Q176533 bioavailability "100.0".
- Q176533 casNumber "71195-58-9".
- Q176533 chEBI "2569".
- Q176533 drugbank "DB00802".
- Q176533 fdaUniiCode "1N74HM2BS7".
- Q176533 iupacName "N-{1-[2-(4-ethyl-5-oxo-4,5-dihydro-1H-1,2,3,4-tetrazol-1-yl)ethyl]-4-(methoxymethyl)piperidin-4-yl}-N-phenylpropanamide".
- Q176533 pubchem "51263".
- Q176533 thumbnail Alfentanil-2D-skeletal.svg?width=300.
- Q176533 wikiPageExternalLink a601130.html.
- Q176533 wikiPageWikiLink Q11068.
- Q176533 wikiPageWikiLink Q12140.
- Q176533 wikiPageWikiLink Q131130.
- Q176533 wikiPageWikiLink Q14911924.
- Q176533 wikiPageWikiLink Q1641494.
- Q176533 wikiPageWikiLink Q173235.
- Q176533 wikiPageWikiLink Q186889.
- Q176533 wikiPageWikiLink Q199602.
- Q176533 wikiPageWikiLink Q407541.
- Q176533 wikiPageWikiLink Q40821.
- Q176533 wikiPageWikiLink Q417902.
- Q176533 wikiPageWikiLink Q427523.
- Q176533 wikiPageWikiLink Q622899.
- Q176533 wikiPageWikiLink Q640448.
- Q176533 wikiPageWikiLink Q6442932.
- Q176533 wikiPageWikiLink Q7029794.
- Q176533 wikiPageWikiLink Q7145146.
- Q176533 wikiPageWikiLink Q7334131.
- Q176533 wikiPageWikiLink Q7486806.
- Q176533 wikiPageWikiLink Q8253301.
- Q176533 wikiPageWikiLink Q8561887.
- Q176533 wikiPageWikiLink Q8645495.
- Q176533 wikiPageWikiLink Q8844648.
- Q176533 wikiPageWikiLink Q8971959.
- Q176533 wikiPageWikiLink Q903523.
- Q176533 wikiPageWikiLink Q9134654.
- Q176533 wikiPageWikiLink Q928770.
- Q176533 wikiPageWikiLink Q9368.
- Q176533 atcPrefix "N01".
- Q176533 atcSuffix "AH02".
- Q176533 bioavailability "100.0".
- Q176533 casNumber "71195".
- Q176533 chebi "2569".
- Q176533 drugbank "DB00802".
- Q176533 iupacName "N-{1-[2-ethyl]-4-piperidin-4-yl}-N-phenylpropanamide".
- Q176533 pubchem "51263".
- Q176533 unii "1".
- Q176533 type ChemicalSubstance.
- Q176533 type Drug.
- Q176533 type ChemicalObject.
- Q176533 type Thing.
- Q176533 type Q8386.
- Q176533 comment "Alfentanil (R-39209, trade name Alfenta, Rapifen in Australia) is a potent but short-acting synthetic opioid analgesic drug, used for anaesthesia in surgery. It is an analogue of fentanyl with around 1/4 to 1/10 the potency of fentanyl and around 1/3 of the duration of action, but with an onset of effects 4x faster than fentanyl. Alfentanil has a pKa of approximately 6.5, which leads to a very high proportion of the drug being uncharged at physiologic pH.".
- Q176533 label "Alfentanil".
- Q176533 depiction Alfentanil-2D-skeletal.svg.