Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q17144671> ?p ?o }
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- Q17144671 subject Q7204727.
- Q17144671 subject Q8802898.
- Q17144671 subject Q9089708.
- Q17144671 abstract "A late protein is a viral protein that is formed after replication of the virus. One example is VP4 from simian virus 40 (SV40).In Human papillomavirus, two late proteins are involved in capsid formation: a major (L1) and a minor (L2) protein, in the approximate proportion 95:5%. L1 forms a pentameric assembly unit of the viral shell in a manner that closely resembles VP1 from polyomaviruses. Intermolecular disulphide bonding holds the L1 capsid proteins together. L1 capsid proteins can bind via its nuclear localisation signal (NLS) to karyopherins Kapbeta(2) and Kapbeta(3) and inhibit the Kapbeta(2) and Kapbeta(3) nuclear import pathways during the productive phase of the viral life cycle. Surface loops on L1 pentamers contain sites of sequence variation between HPV types. L2 minor capsid proteins enter the nucleus twice during infection: in the initial phase after virion disassembly, and in the productive phase when it assembles into replicated virions along with L1 major capsid proteins. L2 proteins contain two nuclear localisation signals (NLSs), one at the N-terminal (nNLS) and the other at the C-terminal (cNLS). L2 uses its NLSs to interact with a network of karyopherins in order to enter the nucleus via several import pathways. L2 from HPV types 11 and 16 was shown to interact with karyopherins Kapbeta(2) and Kapbeta(3). L2 capsid proteins can also interact with viral dsDNA, facilitating its release from the endocytic compartment after viral uncoating.".
- Q17144671 symbol "Late_protein_L1".
- Q17144671 symbol "Late_protein_L2".
- Q17144671 thumbnail PDB_1dzl_EBI.jpg?width=300.
- Q17144671 wikiPageWikiLink Q1648694.
- Q17144671 wikiPageWikiLink Q184627.
- Q17144671 wikiPageWikiLink Q189814.
- Q17144671 wikiPageWikiLink Q284398.
- Q17144671 wikiPageWikiLink Q310425.
- Q17144671 wikiPageWikiLink Q3193641.
- Q17144671 wikiPageWikiLink Q3241872.
- Q17144671 wikiPageWikiLink Q3374897.
- Q17144671 wikiPageWikiLink Q3511065.
- Q17144671 wikiPageWikiLink Q7204727.
- Q17144671 wikiPageWikiLink Q734305.
- Q17144671 wikiPageWikiLink Q7430.
- Q17144671 wikiPageWikiLink Q8054.
- Q17144671 wikiPageWikiLink Q808.
- Q17144671 wikiPageWikiLink Q830465.
- Q17144671 wikiPageWikiLink Q8802898.
- Q17144671 wikiPageWikiLink Q896177.
- Q17144671 wikiPageWikiLink Q9089708.
- Q17144671 wikiPageWikiLink Q910966.
- Q17144671 wikiPageWikiLink Q952587.
- Q17144671 symbol "Late_protein_L1".
- Q17144671 symbol "Late_protein_L2".
- Q17144671 type Biomolecule.
- Q17144671 type Protein.
- Q17144671 type Thing.
- Q17144671 type Q206229.
- Q17144671 type Q8054.
- Q17144671 comment "A late protein is a viral protein that is formed after replication of the virus. One example is VP4 from simian virus 40 (SV40).In Human papillomavirus, two late proteins are involved in capsid formation: a major (L1) and a minor (L2) protein, in the approximate proportion 95:5%. L1 forms a pentameric assembly unit of the viral shell in a manner that closely resembles VP1 from polyomaviruses. Intermolecular disulphide bonding holds the L1 capsid proteins together.".
- Q17144671 label "Late protein".
- Q17144671 depiction PDB_1dzl_EBI.jpg.