Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q17070900> ?p ?o }
Showing triples 1 to 26 of
26
with 100 triples per page.
- Q17070900 subject Q15099846.
- Q17070900 subject Q7237906.
- Q17070900 abstract "Balapiravir (R-1626, Ro4588161) is an experimental antiviral drug which acts as a polymerase inhibitor. There were efforts to develop it as a potential treatment for hepatitis C, and it was subsequently also studied in Dengue fever, but was not found to be useful. Lower doses failed to produce measurable reductions in viral load, while higher doses produced serious side effects such as lymphopenia which precluded further development of the drug. Subsequent research found that excess cytokine production triggered by Dengue virus infection prevented the conversion of the balapiravir prodrug to its active form, thereby blocking the activity of the drug.".
- Q17070900 casNumber "690270-29-2".
- Q17070900 iupacName "[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-2-azido-3,4-bis(2-methylpropanoyloxy)oxolan-2-yl]methyl 2-methylpropanoate".
- Q17070900 pubchem "11691726".
- Q17070900 thumbnail Balapiravir_structure.png?width=300.
- Q17070900 wikiPageWikiLink Q15099846.
- Q17070900 wikiPageWikiLink Q154869.
- Q17070900 wikiPageWikiLink Q212354.
- Q17070900 wikiPageWikiLink Q30953.
- Q17070900 wikiPageWikiLink Q485831.
- Q17070900 wikiPageWikiLink Q603741.
- Q17070900 wikiPageWikiLink Q7226556.
- Q17070900 wikiPageWikiLink Q7237906.
- Q17070900 casNumber "690270".
- Q17070900 iupacName "[-5--2-azido-3,4-bisoxolan-2-yl]methyl 2-methylpropanoate".
- Q17070900 pubchem "11691726".
- Q17070900 type ChemicalSubstance.
- Q17070900 type Drug.
- Q17070900 type ChemicalObject.
- Q17070900 type Thing.
- Q17070900 type Q8386.
- Q17070900 comment "Balapiravir (R-1626, Ro4588161) is an experimental antiviral drug which acts as a polymerase inhibitor. There were efforts to develop it as a potential treatment for hepatitis C, and it was subsequently also studied in Dengue fever, but was not found to be useful. Lower doses failed to produce measurable reductions in viral load, while higher doses produced serious side effects such as lymphopenia which precluded further development of the drug.".
- Q17070900 label "Balapiravir".
- Q17070900 depiction Balapiravir_structure.png.