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- Q17029600 subject Q6938724.
- Q17029600 subject Q7217021.
- Q17029600 abstract "I-TASSER (Iterative Threading ASSEmbly Refinement) is a bioinformatics method for predicting three-dimensional structure model of protein molecules from amino acid sequences. It detects structure templates from the Protein Data Bank by a technique called fold recognition (or threading). The full-length structure models are constructed by reassembling structural fragments from threading templates using replica exchange Monte Carlo simulations. I-TASSER is one of the most successful protein structure prediction methods in the community-wide CASP experiments.I-TASSER has been extended for structure-based protein function predictions, which provides annotations on ligand binding site, gene ontology and enzyme commission by structurally matching structural models of the target protein to the known proteins in protein function databases. It has an on-line server built in the Yang Zhang Lab at the University of Michigan, Ann Arbor, allowing users to submit sequences and obtain structure and function predictions. A standalone package of I-TASSER is available for academic users to download in the I-TASSER website; the commercial version is distributed by NovaFold.".
- Q17029600 thumbnail I-TASSER-pipeline.jpg?width=300.
- Q17029600 wikiPageExternalLink I-TASSER.
- Q17029600 wikiPageExternalLink predictioncenter.org.
- Q17029600 wikiPageExternalLink groups_analysis.cgi?type=server&tbm=on&tbm_hard=on&tbmfm=on&fm=on&submit=Filter.
- Q17029600 wikiPageExternalLink groups_analysis.cgi?target_type=0&gr_type=server&domain_classifications_id=1,2,3,4&field=sum_z_gdt_ts_server_pos.
- Q17029600 wikiPageExternalLink groups.2.html.
- Q17029600 wikiPageExternalLink t-products-NovaFold.aspx.
- Q17029600 wikiPageExternalLink zscores_final.cgi?model_type=first&gr_type=server_only.
- Q17029600 wikiPageExternalLink zhanglab.ccmb.med.umich.edu.
- Q17029600 wikiPageExternalLink I-TASSER.
- Q17029600 wikiPageExternalLink download.
- Q17029600 wikiPageExternalLink README.txt.
- Q17029600 wikiPageExternalLink PSSpred.
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- Q17029600 wikiPageWikiLink Q6938724.
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- Q17029600 name "I-TASSER".
- Q17029600 type CreativeWork.
- Q17029600 type Software.
- Q17029600 type Work.
- Q17029600 type Thing.
- Q17029600 type Q386724.
- Q17029600 type Q7397.
- Q17029600 comment "I-TASSER (Iterative Threading ASSEmbly Refinement) is a bioinformatics method for predicting three-dimensional structure model of protein molecules from amino acid sequences. It detects structure templates from the Protein Data Bank by a technique called fold recognition (or threading). The full-length structure models are constructed by reassembling structural fragments from threading templates using replica exchange Monte Carlo simulations.".
- Q17029600 label "I-TASSER".
- Q17029600 depiction I-TASSER-pipeline.jpg.
- Q17029600 homepage I-TASSER.
- Q17029600 name "I-TASSER".