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- Q17005864 subject Q6240946.
- Q17005864 subject Q6745718.
- Q17005864 subject Q7158325.
- Q17005864 subject Q7478371.
- Q17005864 subject Q8614491.
- Q17005864 subject Q9026237.
- Q17005864 subject Q9052781.
- Q17005864 abstract "Bis-choline tetrathiomolybdate, or WTX101, is a salt of tetrathiomolybdate (TTM, MoS42−) and choline currently under investigation as a therapy against Wilson's disease, a rare and potentially fatal disease in which the body cannot regulate copper. Wilson disease is an autosomal recessive genetic disorder that is manifested by serious hepatic, neurologic or psychiatric symptoms. The disease is fatal if left undiagnosed and untreated. It is estimated that approximately 1 individual in every 15,000 worldwide have Wilson's disease, corresponding to approximately 30,000 individuals in the European Union and approximately 20,000 in the United States.Bis-choline tetrathiomolybdate has been evaluated in clinical trials in patients with various forms of cancer and has received orphan designation in the US and EU as a potential therapy against Wilson disease.Bis-choline salt of tetrathiomolybdate is a de-coppering therapy in clinical development against Wilson disease under the code name WTX101 by Wilson Therapeutics AB. Wilson Therapeutics was founded by HealthCap in 2012.".
- Q17005864 thumbnail Bis-choline_tetrathiomolybdate_(molecular_structure).png?width=300.
- Q17005864 wikiPageExternalLink OOPD_Results_2.cfm?Index_Number=346511.
- Q17005864 wikiPageExternalLink WC500139536.pdf.
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- Q17005864 type ChemicalSubstance.
- Q17005864 type Drug.
- Q17005864 type ChemicalObject.
- Q17005864 type Thing.
- Q17005864 type Q8386.
- Q17005864 comment "Bis-choline tetrathiomolybdate, or WTX101, is a salt of tetrathiomolybdate (TTM, MoS42−) and choline currently under investigation as a therapy against Wilson's disease, a rare and potentially fatal disease in which the body cannot regulate copper. Wilson disease is an autosomal recessive genetic disorder that is manifested by serious hepatic, neurologic or psychiatric symptoms. The disease is fatal if left undiagnosed and untreated.".
- Q17005864 label "Bis-choline tetrathiomolybdate".
- Q17005864 depiction Bis-choline_tetrathiomolybdate_(molecular_structure).png.