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- Q1622337 subject Q8908886.
- Q1622337 abstract "Photostimulation is the use of light to artificially activate biological compounds, cells, tissues, or even whole organisms. Photostimulation can be used to noninvasively probe various relationships between different biological processes, using only light. In the long run, photostimulation has the potential for use in different types of therapy, such as migraine headache. Additionally, photostimulation may be used for the mapping of neuronal connections between different areas of the brain by “uncaging” signaling biomolecules with light. Therapy with photostimulation has been called light therapy, phototherapy, or photobiomodulation.Photostimulation methods fall into two general categories: one set of methods uses light to uncage a compound that then becomes biochemically active, binding to a downstream effector. For example, uncaging glutamate is useful for finding excitatory connections between neurons, since the uncaged glutamate mimics the natural synaptic activity of one neuron impinging upon another. The other major photostimulation method is the use of light to activate a light-sensitive protein such as rhodopsin, which can then excite the cell expressing the opsin.It has been shown that channelrhodopsin-2, a monolithic protein containing a light sensor and a cation channel, provides electrical stimulation of appropriate speed and magnitude to activate neuronal spike firing. Recently, photoinhibition, the inhibition of neural activity with light, has become feasible with the application of molecules such as the light-activated chloride pump halorhodopsin to neural control. Together, blue-light activated channelrhodopsin-2 and the yellow light-activated chloride pump halorhodopsin enable multiple-color, optical activation and silencing of neural activity. (See also Photobiomodulation)".
- Q1622337 thumbnail Photostimulation_of_cAMP.png?width=300.
- Q1622337 wikiPageExternalLink 07.03.han.html.
- Q1622337 wikiPageExternalLink optogenetics.
- Q1622337 wikiPageWikiLink Q127920.
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- Q1622337 wikiPageWikiLink Q210021.
- Q1622337 wikiPageWikiLink Q242310.
- Q1622337 wikiPageWikiLink Q243570.
- Q1622337 wikiPageWikiLink Q2448456.
- Q1622337 wikiPageWikiLink Q38867.
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- Q1622337 wikiPageWikiLink Q706.
- Q1622337 wikiPageWikiLink Q7239.
- Q1622337 wikiPageWikiLink Q7868.
- Q1622337 wikiPageWikiLink Q8054.
- Q1622337 wikiPageWikiLink Q80863.
- Q1622337 wikiPageWikiLink Q8908886.
- Q1622337 wikiPageWikiLink Q905325.
- Q1622337 wikiPageWikiLink Q908981.
- Q1622337 wikiPageWikiLink Q9128.
- Q1622337 wikiPageWikiLink Q9285564.
- Q1622337 comment "Photostimulation is the use of light to artificially activate biological compounds, cells, tissues, or even whole organisms. Photostimulation can be used to noninvasively probe various relationships between different biological processes, using only light. In the long run, photostimulation has the potential for use in different types of therapy, such as migraine headache.".
- Q1622337 label "Photostimulation".
- Q1622337 depiction Photostimulation_of_cAMP.png.