Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q15997123> ?p ?o }
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- Q15997123 subject Q7335318.
- Q15997123 subject Q7467724.
- Q15997123 subject Q8226477.
- Q15997123 subject Q8529504.
- Q15997123 abstract "Senescence-associated beta-galactosidase (SA-β-gal or SABG) is a hypothetical hydrolase enzyme that catalyzes the hydrolysis of β-galactosides into monosaccharides only in senescent cells.Its existence was proposed in 1995 by Dimri et al. following the observation that when beta-galactosidase assays were carried out at pH 6.0, only cells in senescence state develop staining. They proposed a cytochemical assay based on production of a blue-dyed precipitate that results from the cleavage of the chromogenic substrate X-Gal. Since then, even more specific quantitative assays were developed for its detection at pH 6.0.Today this phenomenon is explained by the overexpression and accumulation of the endogenous lysosomal beta-galactosidase specifically in senescent cells. Its expression is not required for senescence. However, it remains as the most widely used biomarker for senescent and aging cells, because it is easy to detect and reliable both in situ and in vitro.".
- Q15997123 arm "p".
- Q15997123 band "22.3".
- Q15997123 chromosome "3".
- Q15997123 ecNumber "3.2.1.23".
- Q15997123 entrezgene "2720".
- Q15997123 hgncid "4298".
- Q15997123 omim "611458".
- Q15997123 refseq "NM_000404".
- Q15997123 symbol "GLB1".
- Q15997123 symbol "SA-β-Gal".
- Q15997123 uniprot "P16278".
- Q15997123 wikiPageExternalLink 8058-2-l.jpg.
- Q15997123 wikiPageExternalLink 8058-2-l.jpg.
- Q15997123 wikiPageWikiLink Q103135.
- Q15997123 wikiPageWikiLink Q133516.
- Q15997123 wikiPageWikiLink Q137154.
- Q15997123 wikiPageWikiLink Q18026074.
- Q15997123 wikiPageWikiLink Q2070979.
- Q15997123 wikiPageWikiLink Q286379.
- Q15997123 wikiPageWikiLink Q7335318.
- Q15997123 wikiPageWikiLink Q7467724.
- Q15997123 wikiPageWikiLink Q8047.
- Q15997123 wikiPageWikiLink Q82264.
- Q15997123 wikiPageWikiLink Q8226477.
- Q15997123 wikiPageWikiLink Q83330.
- Q15997123 wikiPageWikiLink Q8529504.
- Q15997123 wikiPageWikiLink Q96286.
- Q15997123 altsymbols "SA-β-Gal".
- Q15997123 arm "p".
- Q15997123 band "22.3".
- Q15997123 chromosome "3".
- Q15997123 ecnumber "3.2".
- Q15997123 entrezgene "2720".
- Q15997123 hgncid "4298".
- Q15997123 name Q18026074.
- Q15997123 omim "611458".
- Q15997123 refseq "NM_000404".
- Q15997123 symbol Q18026074.
- Q15997123 uniprot "P16278".
- Q15997123 type Biomolecule.
- Q15997123 type Protein.
- Q15997123 type Thing.
- Q15997123 type Q206229.
- Q15997123 type Q8054.
- Q15997123 comment "Senescence-associated beta-galactosidase (SA-β-gal or SABG) is a hypothetical hydrolase enzyme that catalyzes the hydrolysis of β-galactosides into monosaccharides only in senescent cells.Its existence was proposed in 1995 by Dimri et al. following the observation that when beta-galactosidase assays were carried out at pH 6.0, only cells in senescence state develop staining.".
- Q15997123 label "Senescence-associated beta-galactosidase".
- Q15997123 name "galactosidase, beta 1".