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- Q15996797 subject Q8625097.
- Q15996797 abstract "The miR-1 microRNA precursor is a small micro RNA that regulates its target protein's expression in the cell. microRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide products. In this case the mature sequence comes from the 3' arm of the precursor. The mature products are thought to have regulatory roles through complementarity to mRNA. In humans there are two distinct microRNAs that share an identical mature sequence, these are called miR-1-1 and miR-1-2.These micro RNAs have pivotal roles in development and physiology of muscle tissues including the heart. MiR-1 is known to be involved in important role in heart diseases such as hypertrophy, myocardial infarction, and arrhythmias. Studies have shown that MiR-1 is an important regulator of heart adaption after ischemia or ischaemic stress and it is upregulated in the remote myocardium of patients with myocardial infarction. Also MiR-1 is downregulated in myocardial infarcted tissue compared to healthy heart tissue. Plasma levels of MiR-1 can be used as a sensitive biomarker for myocardial infarction.".
- Q15996797 thumbnail RF00103.jpg?width=300.
- Q15996797 wikiPageExternalLink Summary?g=ENSG00000199017;r=20:61151510-61151586;t=ENST00000362147.
- Q15996797 wikiPageExternalLink mirna_entry.pl?acc=MI0000651.
- Q15996797 wikiPageExternalLink entrez?Db=gene&Cmd=retrieve&dopt=full_report&list_uids=406904.
- Q15996797 wikiPageWikiLink Q1148337.
- Q15996797 wikiPageWikiLink Q12152.
- Q15996797 wikiPageWikiLink Q14864102.
- Q15996797 wikiPageWikiLink Q17917651.
- Q15996797 wikiPageWikiLink Q18028479.
- Q15996797 wikiPageWikiLink Q18033993.
- Q15996797 wikiPageWikiLink Q18037154.
- Q15996797 wikiPageWikiLink Q188151.
- Q15996797 wikiPageWikiLink Q188928.
- Q15996797 wikiPageWikiLink Q1898141.
- Q15996797 wikiPageWikiLink Q193825.
- Q15996797 wikiPageWikiLink Q207609.
- Q15996797 wikiPageWikiLink Q223911.
- Q15996797 wikiPageWikiLink Q264118.
- Q15996797 wikiPageWikiLink Q28745.
- Q15996797 wikiPageWikiLink Q310899.
- Q15996797 wikiPageWikiLink Q3272830.
- Q15996797 wikiPageWikiLink Q408174.
- Q15996797 wikiPageWikiLink Q419102.
- Q15996797 wikiPageWikiLink Q494612.
- Q15996797 wikiPageWikiLink Q729.
- Q15996797 wikiPageWikiLink Q8625097.
- Q15996797 comment "The miR-1 microRNA precursor is a small micro RNA that regulates its target protein's expression in the cell. microRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide products. In this case the mature sequence comes from the 3' arm of the precursor. The mature products are thought to have regulatory roles through complementarity to mRNA.".
- Q15996797 label "Mir-1 microRNA precursor family".
- Q15996797 depiction RF00103.jpg.