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- Q155883 subject Q8726644.
- Q155883 abstract "Alfacalcidol (or 1-hydroxycholecalciferol) is an analogue of vitamin D used for supplementation in humans and as a poultry feed additive.Alfacalcidol has a weaker impact on calcium metabolism and parathyroid hormone levels than calcitriol, however alfacalcidol has significant effects on the immune system, including regulatory T cells. It is considered to be a more useful form of vitamin D supplementation, mostly due to much longer half-life and lower kidney load. It is the most commonly prescribed vitamin D metabolite for patients with end stage renal disease, given that impaired renal function alters the ability to carry out the second hydroxylation step required for the formation of the physiologically active form of vitamin D, 1,25-dihydroxyvitamin D3. Alfacalcidol is an active vitamin D3 metabolite, and therefore does not require the second hydroxylation step in the kidney.Used as a poultry feed additive, it prevents tibial dyschondroplasia and increases phytate bioavailability.REDIRECT Template:OR↑ ↑ ↑ ↑ ↑ ↑".
- Q155883 iupacName "(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-7a-Methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol".
- Q155883 thumbnail Alfacalcidol.png?width=300.
- Q155883 wikiPageWikiLink Q1059.
- Q155883 wikiPageWikiLink Q139195.
- Q155883 wikiPageWikiLink Q14860476.
- Q155883 wikiPageWikiLink Q1550619.
- Q155883 wikiPageWikiLink Q175621.
- Q155883 wikiPageWikiLink Q409679.
- Q155883 wikiPageWikiLink Q736715.
- Q155883 wikiPageWikiLink Q7800443.
- Q155883 wikiPageWikiLink Q8726644.
- Q155883 wikiPageWikiLink Q898497.
- Q155883 wikiPageWikiLink Q910704.
- Q155883 wikiPageWikiLink Q9377.
- Q155883 iupacname "-5".
- Q155883 type ChemicalCompound.
- Q155883 type ChemicalSubstance.
- Q155883 type ChemicalObject.
- Q155883 type Thing.
- Q155883 type Q11173.
- Q155883 comment "Alfacalcidol (or 1-hydroxycholecalciferol) is an analogue of vitamin D used for supplementation in humans and as a poultry feed additive.Alfacalcidol has a weaker impact on calcium metabolism and parathyroid hormone levels than calcitriol, however alfacalcidol has significant effects on the immune system, including regulatory T cells. It is considered to be a more useful form of vitamin D supplementation, mostly due to much longer half-life and lower kidney load.".
- Q155883 label "Alfacalcidol".
- Q155883 depiction Alfacalcidol.png.