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- Q15410168 subject Q7211328.
- Q15410168 subject Q8593033.
- Q15410168 subject Q8844648.
- Q15410168 abstract "Zotarolimus (INN, codenamed ABT-578) is an immunosuppressant. It is a semi-synthetic derivative of rapamycin. It was designed for use in stents with phosphorylcholine as a carrier. Coronary stents reduce early complications and improve late clinical outcomes in patients needing interventional cardiology. The first human coronary stent implantation was first performed in 1986 by Puel et al. However, there are complications associated with stent use, development of thrombosis which impedes the efficiency of coronary stents, haemorrhagic and restenosis complications are problems associated with stents.These complications have prompted the development of drug-eluting stents. Stents are bound by a membrane consisting of polymers which not only slowly release zotarolimus and its derivatives into the surrounding tissues but also do not invoke an inflammatory response by the body.Medtronic are using zotarolimus as the anti-proliferative agent in the polymer coating of their Endeavor and Resolute products.".
- Q15410168 atcPrefix "none".
- Q15410168 casNumber "221877-54-9".
- Q15410168 fdaUniiCode "H4GXR80IZE".
- Q15410168 iupacName "(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-10,21-dimethoxy-3-{(1R)-2-[(1S,3R,4S)-3-methoxy-4-(1H-tetrazol-1-yl)cyclohexyl]-1-methylethyl}-6,8,12,14,20,26-hexamethyl-4,9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-heptadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(6H,31H)-pentone".
- Q15410168 thumbnail Zotarolimus.png?width=300.
- Q15410168 wikiPageExternalLink Z-9040.php4.
- Q15410168 wikiPageWikiLink Q10379.
- Q15410168 wikiPageWikiLink Q104116.
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- Q15410168 wikiPageWikiLink Q32089.
- Q15410168 wikiPageWikiLink Q3973120.
- Q15410168 wikiPageWikiLink Q411648.
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- Q15410168 wikiPageWikiLink Q7187582.
- Q15410168 wikiPageWikiLink Q7211328.
- Q15410168 wikiPageWikiLink Q7916461.
- Q15410168 wikiPageWikiLink Q824258.
- Q15410168 wikiPageWikiLink Q8593033.
- Q15410168 wikiPageWikiLink Q8844648.
- Q15410168 wikiPageWikiLink Q898401.
- Q15410168 wikiPageWikiLink Q974135.
- Q15410168 atcPrefix "none".
- Q15410168 casNumber "221877".
- Q15410168 iupacName "-927".
- Q15410168 unii "H4GXR80IZE".
- Q15410168 type ChemicalSubstance.
- Q15410168 type Drug.
- Q15410168 type ChemicalObject.
- Q15410168 type Thing.
- Q15410168 type Q8386.
- Q15410168 comment "Zotarolimus (INN, codenamed ABT-578) is an immunosuppressant. It is a semi-synthetic derivative of rapamycin. It was designed for use in stents with phosphorylcholine as a carrier. Coronary stents reduce early complications and improve late clinical outcomes in patients needing interventional cardiology. The first human coronary stent implantation was first performed in 1986 by Puel et al.".
- Q15410168 label "Zotarolimus".
- Q15410168 depiction Zotarolimus.png.