Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q1536513> ?p ?o }
- Q1536513 subject Q5601738.
- Q1536513 subject Q8380722.
- Q1536513 abstract "Focal infection theory (FIT) explains that a localized infection, often asymptomatic, can disseminate microorganisms or their toxins to distant sites within the body, and thereby initiate disease. The resulting diseases are often systemic and chronic, but usually not thought infectious, such as arthritis, atherosclerosis, cancer, or mental illness. (Distant injury is focal infection's key principle, whereas in ordinary infectious disease, the infection itself is systemic, as in measles, or the initially infected site is readily identifiable and invasion progresses contiguously, as in gangrene.) This ancient concept took modern form around 1900, and was widely accepted in Anglosphere medicine by the 1920s.In the theory, the focus of infection is often unrecognized, while secondary infections might occur at sites particularly susceptible to such microbial species or toxin. Several locations were commonly claimed as foci—appendix, urinary bladder, gall bladder, kidney, liver, prostate, and nasal sinus—but most commonly oral tissues. Not only chronically infected tonsils and dental decay, but also sites of dental restoration and root canal therapy were indicted as the foci. The putative oral sepsis was countered by tonsillectomies and tooth extractions, including of endodontically treated teeth and even of apparently healthy teeth, newly popular approaches—sometimes leaving individuals toothless—to treat or prevent diverse chronic diseases.Drawing severe criticism in the 1930s, focal infection theory, whose popularity zealously exceeded consensus evidence, was generally discarded in the 1940s amid overwhelming consensus of its general falsity, whereupon dental restorations and root canal therapy became again favored. Untreated endodontic disease retained recognition as fostering systemic disease, but only alternative medicine and later biological dentistry continued highlighting sites of dental treatment—root canal therapy, dental implant, and, as newly claimed, tooth extraction, too—as foci of infection promoting systemic diseases. The primary recognition of focal infection is endocarditis if oral bacteria enter blood and infect the heart, perhaps its valves.Entering the 21st century, scientific evidence supporting general relevance of focal infection theory remained slim, yet evolved understandings of disease mechanisms had established a third possible mechanism—altogether, metastasis of infection, metastatic toxic injury, and, as recently revealed, metastatic immunologic injury—that might occur simultaneously and even interact. Meanwhile, focal infection theory has gained renewed attention, as dental infections apparently are widespread and significant contributors to systemic diseases, although mainstream attention is on ordinary periodontal disease, not hypotheses of stealth infections via dental treatment. Despite some doubts renewed in the 1990s by critics of conventional dentistry, dentistry scholars maintain that endodontic therapy can be performed without creating focal infections.".
- Q1536513 wikiPageWikiLink Q101896.
- Q1536513 wikiPageWikiLink Q101929.
- Q1536513 wikiPageWikiLink Q103537.
- Q1536513 wikiPageWikiLink Q1054718.
- Q1536513 wikiPageWikiLink Q1059765.
- Q1536513 wikiPageWikiLink Q1064894.
- Q1536513 wikiPageWikiLink Q107647.
- Q1536513 wikiPageWikiLink Q11083.
- Q1536513 wikiPageWikiLink Q1110546.
- Q1536513 wikiPageWikiLink Q1125312.
- Q1536513 wikiPageWikiLink Q1129007.
- Q1536513 wikiPageWikiLink Q1130172.
- Q1536513 wikiPageWikiLink Q1135939.
- Q1536513 wikiPageWikiLink Q1137326.
- Q1536513 wikiPageWikiLink Q121610.
- Q1536513 wikiPageWikiLink Q12187.
- Q1536513 wikiPageWikiLink Q12192.
- Q1536513 wikiPageWikiLink Q12204.
- Q1536513 wikiPageWikiLink Q131755.
- Q1536513 wikiPageWikiLink Q1330402.
- Q1536513 wikiPageWikiLink Q133805.
- Q1536513 wikiPageWikiLink Q1350388.
- Q1536513 wikiPageWikiLink Q1355267.
- Q1536513 wikiPageWikiLink Q1373376.
- Q1536513 wikiPageWikiLink Q141440.
- Q1536513 wikiPageWikiLink Q1414805.
- Q1536513 wikiPageWikiLink Q143680.
- Q1536513 wikiPageWikiLink Q1468920.
- Q1536513 wikiPageWikiLink Q1470970.
- Q1536513 wikiPageWikiLink Q147778.
- Q1536513 wikiPageWikiLink Q1536513.
- Q1536513 wikiPageWikiLink Q156318.
- Q1536513 wikiPageWikiLink Q15631877.
- Q1536513 wikiPageWikiLink Q15995342.
- Q1536513 wikiPageWikiLink Q16026210.
- Q1536513 wikiPageWikiLink Q1606627.
- Q1536513 wikiPageWikiLink Q1637017.
- Q1536513 wikiPageWikiLink Q1645075.
- Q1536513 wikiPageWikiLink Q168805.
- Q1536513 wikiPageWikiLink Q170381.
- Q1536513 wikiPageWikiLink Q172254.
- Q1536513 wikiPageWikiLink Q176741.
- Q1536513 wikiPageWikiLink Q1774898.
- Q1536513 wikiPageWikiLink Q1779148.
- Q1536513 wikiPageWikiLink Q1816730.
- Q1536513 wikiPageWikiLink Q181876.
- Q1536513 wikiPageWikiLink Q18207173.
- Q1536513 wikiPageWikiLink Q183130.
- Q1536513 wikiPageWikiLink Q183134.
- Q1536513 wikiPageWikiLink Q187117.
- Q1536513 wikiPageWikiLink Q187255.
- Q1536513 wikiPageWikiLink Q188151.
- Q1536513 wikiPageWikiLink Q188504.
- Q1536513 wikiPageWikiLink Q193727.
- Q1536513 wikiPageWikiLink Q1996053.
- Q1536513 wikiPageWikiLink Q201492.
- Q1536513 wikiPageWikiLink Q203337.
- Q1536513 wikiPageWikiLink Q21042825.
- Q1536513 wikiPageWikiLink Q210975.
- Q1536513 wikiPageWikiLink Q212961.
- Q1536513 wikiPageWikiLink Q215620.
- Q1536513 wikiPageWikiLink Q2453464.
- Q1536513 wikiPageWikiLink Q269334.
- Q1536513 wikiPageWikiLink Q2782326.
- Q1536513 wikiPageWikiLink Q281473.
- Q1536513 wikiPageWikiLink Q28797.
- Q1536513 wikiPageWikiLink Q30612.
- Q1536513 wikiPageWikiLink Q325253.
- Q1536513 wikiPageWikiLink Q327373.
- Q1536513 wikiPageWikiLink Q3381857.
- Q1536513 wikiPageWikiLink Q3472282.
- Q1536513 wikiPageWikiLink Q34740.
- Q1536513 wikiPageWikiLink Q360236.
- Q1536513 wikiPageWikiLink Q369668.
- Q1536513 wikiPageWikiLink Q37187.
- Q1536513 wikiPageWikiLink Q37193.
- Q1536513 wikiPageWikiLink Q380036.
- Q1536513 wikiPageWikiLink Q389735.
- Q1536513 wikiPageWikiLink Q391083.
- Q1536513 wikiPageWikiLink Q3922751.
- Q1536513 wikiPageWikiLink Q39631.
- Q1536513 wikiPageWikiLink Q41083.
- Q1536513 wikiPageWikiLink Q41112.
- Q1536513 wikiPageWikiLink Q411398.
- Q1536513 wikiPageWikiLink Q41506.
- Q1536513 wikiPageWikiLink Q41630.
- Q1536513 wikiPageWikiLink Q423261.
- Q1536513 wikiPageWikiLink Q428253.
- Q1536513 wikiPageWikiLink Q466524.
- Q1536513 wikiPageWikiLink Q4743596.
- Q1536513 wikiPageWikiLink Q48286.
- Q1536513 wikiPageWikiLink Q5133860.
- Q1536513 wikiPageWikiLink Q5264.
- Q1536513 wikiPageWikiLink Q529.
- Q1536513 wikiPageWikiLink Q540092.
- Q1536513 wikiPageWikiLink Q541576.
- Q1536513 wikiPageWikiLink Q5601738.