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- Q14905348 subject Q7279730.
- Q14905348 abstract "Heparin cofactor II (HCII), a protein encoded by the SERPIND1 gene, is a coagulation factor that inhibits IIa, and is a cofactor for heparin and dermatan sulfate ("minor antithrombin"). The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency.Heparin Cofactor II deficiency can lead to increased thrombin generation and a hypercoagulable state.".
- Q14905348 entrezgene "3053".
- Q14905348 wikiPageExternalLink merops.cgi?id=I04.019.
- Q14905348 wikiPageWikiLink Q179217.
- Q14905348 wikiPageWikiLink Q190016.
- Q14905348 wikiPageWikiLink Q2335618.
- Q14905348 wikiPageWikiLink Q25712.
- Q14905348 wikiPageWikiLink Q7279730.
- Q14905348 type Biomolecule.
- Q14905348 type Protein.
- Q14905348 type Thing.
- Q14905348 type Q206229.
- Q14905348 type Q8054.
- Q14905348 comment "Heparin cofactor II (HCII), a protein encoded by the SERPIND1 gene, is a coagulation factor that inhibits IIa, and is a cofactor for heparin and dermatan sulfate ("minor antithrombin"). The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily.".
- Q14905348 label "Heparin cofactor II".