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- Q14859656 subject Q6585528.
- Q14859656 subject Q7153057.
- Q14859656 subject Q7177888.
- Q14859656 subject Q8482243.
- Q14859656 abstract "Intrinsic factor (IF), also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells of the stomach. It is necessary for the absorption of vitamin B12 (cobalamin) later on in the small intestine. In humans, the gastric intrinsic factor protein is encoded by the GIF gene.Haptocorrin (also known as HC, R protein, and transcobalamin I, TCN1), is a glycoprotein secreted by the salivary glands which binds to vitamin B12. Vitamin B12 is acid sensitive and in binding to transcobalamin I it can safely pass through the acidic stomach to the duodenum. Here in the less acidic environment of the small intestine, pancreatic enzymes digest the glycoprotein carrier and vitamin B12 can then bind to intrinsic factor. This new complex is then absorbed by the epithelial cells (enterocytes) of the ileum. Inside the cells, B12 dissociates once again and binds to another protein, transcobalamin II (TCN2). The new complex can then exit the epithelial cells to be carried to the liver.".
- Q14859656 entrezgene "2694".
- Q14859656 wikiPageExternalLink intrinsic_factor.html.
- Q14859656 wikiPageWikiLink Q1029907.
- Q14859656 wikiPageWikiLink Q10832211.
- Q14859656 wikiPageWikiLink Q1340349.
- Q14859656 wikiPageWikiLink Q1346016.
- Q14859656 wikiPageWikiLink Q134938.
- Q14859656 wikiPageWikiLink Q134955.
- Q14859656 wikiPageWikiLink Q1442923.
- Q14859656 wikiPageWikiLink Q1640093.
- Q14859656 wikiPageWikiLink Q18031883.
- Q14859656 wikiPageWikiLink Q1826391.
- Q14859656 wikiPageWikiLink Q187126.
- Q14859656 wikiPageWikiLink Q187706.
- Q14859656 wikiPageWikiLink Q190265.
- Q14859656 wikiPageWikiLink Q2409.
- Q14859656 wikiPageWikiLink Q3329800.
- Q14859656 wikiPageWikiLink Q357503.
- Q14859656 wikiPageWikiLink Q411927.
- Q14859656 wikiPageWikiLink Q641605.
- Q14859656 wikiPageWikiLink Q6585528.
- Q14859656 wikiPageWikiLink Q7153057.
- Q14859656 wikiPageWikiLink Q7177888.
- Q14859656 wikiPageWikiLink Q7187.
- Q14859656 wikiPageWikiLink Q784720.
- Q14859656 wikiPageWikiLink Q785022.
- Q14859656 wikiPageWikiLink Q8054.
- Q14859656 wikiPageWikiLink Q8084905.
- Q14859656 wikiPageWikiLink Q8482243.
- Q14859656 type Biomolecule.
- Q14859656 type Protein.
- Q14859656 type Thing.
- Q14859656 type Q206229.
- Q14859656 type Q8054.
- Q14859656 comment "Intrinsic factor (IF), also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells of the stomach. It is necessary for the absorption of vitamin B12 (cobalamin) later on in the small intestine. In humans, the gastric intrinsic factor protein is encoded by the GIF gene.Haptocorrin (also known as HC, R protein, and transcobalamin I, TCN1), is a glycoprotein secreted by the salivary glands which binds to vitamin B12.".
- Q14859656 label "Intrinsic factor".