Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q13415380> ?p ?o }
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- Q13415380 subject Q7334142.
- Q13415380 subject Q8256511.
- Q13415380 subject Q8281823.
- Q13415380 subject Q8297737.
- Q13415380 abstract "Tiospirone (BMY-13,859), also sometimes called tiaspirone or tiosperone, is an atypical antipsychotic of the azapirone class. It was investigated as a treatment for schizophrenia in the late 1980s and was found to have an effectiveness equivalent to those of typical antipsychotics in clinical trials but without causing extrapyramidal side effects. However, development was halted and it was not marketed. Perospirone, another azapirone derivative with antipsychotic properties, was synthesized and assayed several years after tiospirone. It was found to be both more potent and more selective in comparison and was commercialized instead.Tiospirone acts as a 5-HT1A receptor partial agonist, 5-HT2A, 5-HT2C, and 5-HT7 receptor inverse agonist, and D2, D4, and α1-adrenergic receptor antagonist.Binding profile".
- Q13415380 atcPrefix "none".
- Q13415380 casNumber "87691-91-6".
- Q13415380 fdaUniiCode "35C6UMO5SR".
- Q13415380 iupacName "8-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-8-azaspiro[4.5]decane-7,9-dione".
- Q13415380 pubchem "55752".
- Q13415380 thumbnail Tiospirone.svg?width=300.
- Q13415380 wikiPageWikiLink Q1258877.
- Q13415380 wikiPageWikiLink Q1385411.
- Q13415380 wikiPageWikiLink Q14866071.
- Q13415380 wikiPageWikiLink Q14891424.
- Q13415380 wikiPageWikiLink Q15335165.
- Q13415380 wikiPageWikiLink Q1671731.
- Q13415380 wikiPageWikiLink Q18027437.
- Q13415380 wikiPageWikiLink Q18027451.
- Q13415380 wikiPageWikiLink Q2066956.
- Q13415380 wikiPageWikiLink Q238509.
- Q13415380 wikiPageWikiLink Q2554162.
- Q13415380 wikiPageWikiLink Q288060.
- Q13415380 wikiPageWikiLink Q30612.
- Q13415380 wikiPageWikiLink Q3269441.
- Q13415380 wikiPageWikiLink Q410943.
- Q13415380 wikiPageWikiLink Q41112.
- Q13415380 wikiPageWikiLink Q4352014.
- Q13415380 wikiPageWikiLink Q6590349.
- Q13415380 wikiPageWikiLink Q7334142.
- Q13415380 wikiPageWikiLink Q758295.
- Q13415380 wikiPageWikiLink Q770260.
- Q13415380 wikiPageWikiLink Q8256511.
- Q13415380 wikiPageWikiLink Q8281823.
- Q13415380 wikiPageWikiLink Q8297737.
- Q13415380 atcPrefix "none".
- Q13415380 casNumber "87691".
- Q13415380 iupacName "8".
- Q13415380 pubchem "55752".
- Q13415380 unii "35".
- Q13415380 type ChemicalSubstance.
- Q13415380 type Drug.
- Q13415380 type ChemicalObject.
- Q13415380 type Thing.
- Q13415380 type Q8386.
- Q13415380 comment "Tiospirone (BMY-13,859), also sometimes called tiaspirone or tiosperone, is an atypical antipsychotic of the azapirone class. It was investigated as a treatment for schizophrenia in the late 1980s and was found to have an effectiveness equivalent to those of typical antipsychotics in clinical trials but without causing extrapyramidal side effects. However, development was halted and it was not marketed.".
- Q13415380 label "Tiospirone".
- Q13415380 depiction Tiospirone.svg.