Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q1259458> ?p ?o }
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- Q1259458 subject Q8255706.
- Q1259458 subject Q8529119.
- Q1259458 subject Q8760074.
- Q1259458 subject Q8791920.
- Q1259458 subject Q9052323.
- Q1259458 abstract "Sorbinil is an aldose reductase inhibitor being investigated for treatment of diabetic complications including neuropathy and retinopathy. Aldose reductase is an enzyme present in lens and brain that gets rid of excess glucose by converting it to sorbitol. Sorbitol accumulation can lead to the development of cataracts in the lens and neuropathy in peripheral nerves. Sorbinil has been shown to inhibit aldose reductase in human brain and placenta and calf and rat lens. Sorbinil reduced sorbitol accummulation in rat lens and sciatic nerve of diabetic rats orally administered 0.25mg/kg sorbinil.".
- Q1259458 iupacName "(4S)-6-Fluoro-2,3-dihydro-2’H,5’H-spiro[chromene-4,4’-imidazolidine]-2’,5’-dione".
- Q1259458 thumbnail Sorbinil.svg?width=300.
- Q1259458 wikiPageWikiLink Q1073.
- Q1259458 wikiPageWikiLink Q1212935.
- Q1259458 wikiPageWikiLink Q127724.
- Q1259458 wikiPageWikiLink Q146701.
- Q1259458 wikiPageWikiLink Q245280.
- Q1259458 wikiPageWikiLink Q307869.
- Q1259458 wikiPageWikiLink Q37525.
- Q1259458 wikiPageWikiLink Q414213.
- Q1259458 wikiPageWikiLink Q427492.
- Q1259458 wikiPageWikiLink Q550455.
- Q1259458 wikiPageWikiLink Q8047.
- Q1259458 wikiPageWikiLink Q8255706.
- Q1259458 wikiPageWikiLink Q8529119.
- Q1259458 wikiPageWikiLink Q8760074.
- Q1259458 wikiPageWikiLink Q8791920.
- Q1259458 wikiPageWikiLink Q9052323.
- Q1259458 wikiPageWikiLink Q945238.
- Q1259458 wikiPageWikiLink Q9620.
- Q1259458 iupacname "-6".
- Q1259458 type ChemicalCompound.
- Q1259458 type ChemicalSubstance.
- Q1259458 type ChemicalObject.
- Q1259458 type Thing.
- Q1259458 type Q11173.
- Q1259458 comment "Sorbinil is an aldose reductase inhibitor being investigated for treatment of diabetic complications including neuropathy and retinopathy. Aldose reductase is an enzyme present in lens and brain that gets rid of excess glucose by converting it to sorbitol. Sorbitol accumulation can lead to the development of cataracts in the lens and neuropathy in peripheral nerves. Sorbinil has been shown to inhibit aldose reductase in human brain and placenta and calf and rat lens.".
- Q1259458 label "Sorbinil".
- Q1259458 depiction Sorbinil.svg.