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- Q1216264 subject Q15645290.
- Q1216264 subject Q15805258.
- Q1216264 subject Q7337151.
- Q1216264 subject Q7416722.
- Q1216264 abstract "Nelarabine is a chemotherapy drug used in T-cell acute lymphoblastic leukemia. It was previously known as 506U78.Nelarabine is a purine nucleoside analog converted to its corresponding arabinosylguanine nucleotide triphosphate (araGTP), resulting in inhibition of DNA synthesis and cytotoxicity. Pre-clinical studies suggest that T-cells are particularly sensitive to nelarabine. In October 2005, it was approved by the FDA for acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma that has not responded to or has relapsed following treatment with at least two chemotherapy regimens. It was later approved in the European Union in the October of 2005. Complete responses have been achieved with this medication.It is marketed in the US as Arranon and as Atriance in the EU by Novartis.".
- Q1216264 atcPrefix "L01".
- Q1216264 atcSuffix "BB07".
- Q1216264 casNumber "121032-29-9".
- Q1216264 drugbank "DB01280".
- Q1216264 fdaUniiCode "60158CV180".
- Q1216264 iupacName "(2R,3S,4S,5R)-2-(2-amino-6-methoxy-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol".
- Q1216264 pubchem "3011155".
- Q1216264 thumbnail Nelarabine_structure.svg?width=300.
- Q1216264 wikiPageWikiLink Q14864787.
- Q1216264 wikiPageWikiLink Q15645290.
- Q1216264 wikiPageWikiLink Q15805258.
- Q1216264 wikiPageWikiLink Q188261.
- Q1216264 wikiPageWikiLink Q28734.
- Q1216264 wikiPageWikiLink Q458.
- Q1216264 wikiPageWikiLink Q507154.
- Q1216264 wikiPageWikiLink Q5205774.
- Q1216264 wikiPageWikiLink Q640448.
- Q1216264 wikiPageWikiLink Q7239590.
- Q1216264 wikiPageWikiLink Q7337151.
- Q1216264 wikiPageWikiLink Q7416722.
- Q1216264 wikiPageWikiLink Q9377.
- Q1216264 wikiPageWikiLink Q974135.
- Q1216264 atcPrefix "L01".
- Q1216264 atcSuffix "BB07".
- Q1216264 casNumber "121032".
- Q1216264 drugbank "DB01280".
- Q1216264 iupacName "-2".
- Q1216264 pubchem "3011155".
- Q1216264 unii "60158".
- Q1216264 type ChemicalSubstance.
- Q1216264 type Drug.
- Q1216264 type ChemicalObject.
- Q1216264 type Thing.
- Q1216264 type Q8386.
- Q1216264 comment "Nelarabine is a chemotherapy drug used in T-cell acute lymphoblastic leukemia. It was previously known as 506U78.Nelarabine is a purine nucleoside analog converted to its corresponding arabinosylguanine nucleotide triphosphate (araGTP), resulting in inhibition of DNA synthesis and cytotoxicity. Pre-clinical studies suggest that T-cells are particularly sensitive to nelarabine.".
- Q1216264 label "Nelarabine".
- Q1216264 depiction Nelarabine_structure.svg.