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- Q1185869 subject Q6193293.
- Q1185869 subject Q7081681.
- Q1185869 subject Q7130316.
- Q1185869 subject Q8620875.
- Q1185869 abstract "An inhibitory postsynaptic potential (IPSP) is a kind of synaptic potential that makes a postsynaptic neuron less likely to generate an action potential. The opposite of an inhibitory postsynaptic potential is an excitatory postsynaptic potential (EPSP), which is a synaptic potential that makes a postsynaptic neuron more likely to generate an action potential. They can take place at all chemical synapses, which use the secretion of neurotransmitters to create cell to cell signalling. Inhibitory presynaptic neurons release neurotransmitters that then bind to the postsynaptic receptors; this induces a postsynaptic conductance change as ion channels open or close. An electric current that changes the postsynaptic membrane potential to create a more negative postsynaptic potential is generated. Depolarization can also occur due to an IPSP if the reverse potential is between the resting threshold and the action potential threshold. Another way to look at inhibitory postsynaptic potentials is that they are also a chloride conductance change in the neuronal cell because it decreases the driving force.Microelectrodes can be used to measure postsynaptic potentials at either excitatory or inhibitory synapses.In general, a postsynaptic potential is dependent on the type and combination of receptor channel, reverse potential of the postsynaptic potential, action potential threshold voltage, ionic permeability of the ion channel, as well as the concentrations of the ions in and out of the cell; this determines if it is excitatory or inhibitory. IPSPs always want to keep the membrane potential more negative than the action potential threshold and can be seen as a “transient hyperpolarization”. EPSPs and IPSPs compete with each other at numerous synapses of a neuron; this determines whether or not the action potential at the presynaptic terminal will regenerate at the postsynaptic membrane. Some common neurotransmitters involved in IPSPs are GABA and glycine.".
- Q1185869 thumbnail IPSPflowchart.jpg?width=300.
- Q1185869 wikiPageWikiLink Q1207387.
- Q1185869 wikiPageWikiLink Q1355864.
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- Q1185869 wikiPageWikiLink Q16979465.
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- Q1185869 wikiPageWikiLink Q181136.
- Q1185869 wikiPageWikiLink Q194277.
- Q1185869 wikiPageWikiLink Q206348.
- Q1185869 wikiPageWikiLink Q210021.
- Q1185869 wikiPageWikiLink Q2365287.
- Q1185869 wikiPageWikiLink Q2643251.
- Q1185869 wikiPageWikiLink Q407241.
- Q1185869 wikiPageWikiLink Q407438.
- Q1185869 wikiPageWikiLink Q409632.
- Q1185869 wikiPageWikiLink Q416602.
- Q1185869 wikiPageWikiLink Q418536.
- Q1185869 wikiPageWikiLink Q43054.
- Q1185869 wikiPageWikiLink Q48360.
- Q1185869 wikiPageWikiLink Q6193293.
- Q1185869 wikiPageWikiLink Q620730.
- Q1185869 wikiPageWikiLink Q644945.
- Q1185869 wikiPageWikiLink Q7049590.
- Q1185869 wikiPageWikiLink Q7081681.
- Q1185869 wikiPageWikiLink Q7130316.
- Q1185869 wikiPageWikiLink Q7662040.
- Q1185869 wikiPageWikiLink Q83183.
- Q1185869 wikiPageWikiLink Q83871.
- Q1185869 wikiPageWikiLink Q8620875.
- Q1185869 wikiPageWikiLink Q863533.
- Q1185869 wikiPageWikiLink Q901988.
- Q1185869 wikiPageWikiLink Q9606.
- Q1185869 comment "An inhibitory postsynaptic potential (IPSP) is a kind of synaptic potential that makes a postsynaptic neuron less likely to generate an action potential. The opposite of an inhibitory postsynaptic potential is an excitatory postsynaptic potential (EPSP), which is a synaptic potential that makes a postsynaptic neuron more likely to generate an action potential. They can take place at all chemical synapses, which use the secretion of neurotransmitters to create cell to cell signalling.".
- Q1185869 label "Inhibitory postsynaptic potential".
- Q1185869 depiction IPSPflowchart.jpg.