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- Q1149618 subject Q8420115.
- Q1149618 abstract "Toxic equivalency factor (TEF) expresses the toxicity of dioxins, furans and PCBs in terms of the most toxic form of dioxin, 2,3,7,8-TCDD. The toxicity of the individual congeners may vary by orders of magnitude.With the TEFs, the toxicity of a mixture of dioxins and dioxin-like compounds can be expressed in a single number - the toxic equivalency (TEQ). It is a single figure resulting from the product of the concentration and individual TEF values of each congener.The TEF/TEQ concept has been developed to facilitate risk assessment and regulatory control. While the initial and current set of TEFs only apply to dioxins and dioxin-like chemicals (DLCs), the concept can theoretically be applied to any group of chemicals satisfying the extensive similarity criteria used with dioxins, primarily that the main mechanism of action is shared across the group. Thus far, only the DLCs have had such a high degree of evidence of toxicological similarity.There have been several systems over the years in operation, such as the International Toxic Equivalents for dioxins and furans only, represented as I-TEQDF, as well as several country-specific TEFs. The present World Health Organisation scheme, represented as WHO-TEQDFP, which includes PCBs is now universally accepted.".
- Q1149618 wikiPageExternalLink tri4339.htm.
- Q1149618 wikiPageExternalLink 6B7ECFWdh.
- Q1149618 wikiPageWikiLink Q1057.
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- Q1149618 wikiPageWikiLink Q410943.
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- Q1149618 wikiPageWikiLink Q518730.
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- Q1149618 wikiPageWikiLink Q540614.
- Q1149618 wikiPageWikiLink Q6888113.
- Q1149618 wikiPageWikiLink Q7817.
- Q1149618 wikiPageWikiLink Q8420115.
- Q1149618 wikiPageWikiLink Q900891.
- Q1149618 comment "Toxic equivalency factor (TEF) expresses the toxicity of dioxins, furans and PCBs in terms of the most toxic form of dioxin, 2,3,7,8-TCDD. The toxicity of the individual congeners may vary by orders of magnitude.With the TEFs, the toxicity of a mixture of dioxins and dioxin-like compounds can be expressed in a single number - the toxic equivalency (TEQ).".
- Q1149618 label "Toxic equivalency factor".