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- Q10858994 subject Q52319.
- Q10858994 subject Q7162167.
- Q10858994 subject Q8839994.
- Q10858994 abstract "Moxestrol (INN) (brand name Surestryl), also known as 11β-methoxy-17α-ethinyl-1,3,5(10)-estratriene-3,17β-diol or as 11β-methoxy-17α-ethinylestradiol, is a synthetic, steroidal estrogen that is or was used in Europe for the treatment of menopausal symptoms. It is the 11β-methoxy derivative of ethinyl estradiol, and is one of the most potent estrogens known, being some 10–100 times more potent than estradiol and about 5-fold more potent than ethinyl estradiol. The very high potency of moxestrol has been attributed to its high affinity for the estrogen receptor (ER), its negligible plasma binding to sex hormone binding globulin and low binding to serum albumin, and its lower relative rate of metabolization. In contrast to estradiol, which has roughly the same affinity for both ERs (Ki 0.12 nM and 0.15 nM, respectively), moxestrol possesses several-fold selectivity for ERα (Ki = 0.50 nM) over ERβ (Ki = 2.6 nM).".
- Q10858994 atcPrefix "G03".
- Q10858994 atcSuffix "CB04".
- Q10858994 bioavailability "33.0".
- Q10858994 casNumber "34816-55-2".
- Q10858994 iupacName "(8S,9S,11S,13S,14S,17R)-17-ethynyl-11-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol".
- Q10858994 pubchem "11954041".
- Q10858994 thumbnail Moxestrol_structure.svg?width=300.
- Q10858994 wikiPageWikiLink Q1057.
- Q10858994 wikiPageWikiLink Q14865325.
- Q10858994 wikiPageWikiLink Q14902310.
- Q10858994 wikiPageWikiLink Q15329133.
- Q10858994 wikiPageWikiLink Q167149.
- Q10858994 wikiPageWikiLink Q174211.
- Q10858994 wikiPageWikiLink Q177708.
- Q10858994 wikiPageWikiLink Q177911.
- Q10858994 wikiPageWikiLink Q2066956.
- Q10858994 wikiPageWikiLink Q277954.
- Q10858994 wikiPageWikiLink Q285166.
- Q10858994 wikiPageWikiLink Q3927871.
- Q10858994 wikiPageWikiLink Q415563.
- Q10858994 wikiPageWikiLink Q416496.
- Q10858994 wikiPageWikiLink Q422416.
- Q10858994 wikiPageWikiLink Q424232.
- Q10858994 wikiPageWikiLink Q46.
- Q10858994 wikiPageWikiLink Q52319.
- Q10858994 wikiPageWikiLink Q7162167.
- Q10858994 wikiPageWikiLink Q824258.
- Q10858994 wikiPageWikiLink Q8839994.
- Q10858994 wikiPageWikiLink Q899107.
- Q10858994 wikiPageWikiLink Q904308.
- Q10858994 atcPrefix "G03".
- Q10858994 atcSuffix "CB04".
- Q10858994 bioavailability "33.0".
- Q10858994 casNumber "34816".
- Q10858994 iupacName "-17".
- Q10858994 pubchem "11954041".
- Q10858994 type ChemicalSubstance.
- Q10858994 type Drug.
- Q10858994 type ChemicalObject.
- Q10858994 type Thing.
- Q10858994 type Q8386.
- Q10858994 comment "Moxestrol (INN) (brand name Surestryl), also known as 11β-methoxy-17α-ethinyl-1,3,5(10)-estratriene-3,17β-diol or as 11β-methoxy-17α-ethinylestradiol, is a synthetic, steroidal estrogen that is or was used in Europe for the treatment of menopausal symptoms. It is the 11β-methoxy derivative of ethinyl estradiol, and is one of the most potent estrogens known, being some 10–100 times more potent than estradiol and about 5-fold more potent than ethinyl estradiol.".
- Q10858994 label "Moxestrol".
- Q10858994 depiction Moxestrol_structure.svg.