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- Q1063862 subject Q7469566.
- Q1063862 subject Q8255322.
- Q1063862 abstract "Idarubicin /ˌaɪdəˈruːbᵻsɪn/ or 4-demethoxydaunorubicin is an anthracycline antileukemic drug. It inserts itself into DNA and prevents DNA unwinding by interfering with the enzyme topoisomerase II. It is an analog of daunorubicin, but the absence of a methoxy group increases its fat solubility and cellular uptake.Similar to other anthracyclines, it also induces histone eviction from chromatin.It belongs to the family of drugs called antitumor antibiotics. It is currently combined with cytosine arabinoside as a first line treatment of acute myeloid leukemia. It is distributed under the trade names Zavedos (UK) and Idamycin (USA).".
- Q1063862 atcPrefix "L01".
- Q1063862 atcSuffix "DB06".
- Q1063862 casNumber "58957-92-9".
- Q1063862 chEBI "42068".
- Q1063862 drugbank "DB01177".
- Q1063862 fdaUniiCode "ZRP63D75JW".
- Q1063862 iupacName "(1S,3S)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxo-α-(L)-lyxo-hexopyranoside".
- Q1063862 pubchem "42890".
- Q1063862 thumbnail Idarubicin.svg?width=300.
- Q1063862 wikiPageExternalLink ?ligand=DM5.
- Q1063862 wikiPageWikiLink Q180951.
- Q1063862 wikiPageWikiLink Q180983.
- Q1063862 wikiPageWikiLink Q264118.
- Q1063862 wikiPageWikiLink Q36293.
- Q1063862 wikiPageWikiLink Q411659.
- Q1063862 wikiPageWikiLink Q411991.
- Q1063862 wikiPageWikiLink Q417589.
- Q1063862 wikiPageWikiLink Q4774880.
- Q1063862 wikiPageWikiLink Q7469566.
- Q1063862 wikiPageWikiLink Q766195.
- Q1063862 wikiPageWikiLink Q8255322.
- Q1063862 wikiPageWikiLink Q974135.
- Q1063862 atcPrefix "L01".
- Q1063862 atcSuffix "DB06".
- Q1063862 casNumber "58957".
- Q1063862 chebi "42068".
- Q1063862 drugbank "DB01177".
- Q1063862 iupacName "-3".
- Q1063862 pubchem "42890".
- Q1063862 unii "ZRP63D75JW".
- Q1063862 type ChemicalSubstance.
- Q1063862 type Drug.
- Q1063862 type ChemicalObject.
- Q1063862 type Thing.
- Q1063862 type Q8386.
- Q1063862 comment "Idarubicin /ˌaɪdəˈruːbᵻsɪn/ or 4-demethoxydaunorubicin is an anthracycline antileukemic drug. It inserts itself into DNA and prevents DNA unwinding by interfering with the enzyme topoisomerase II. It is an analog of daunorubicin, but the absence of a methoxy group increases its fat solubility and cellular uptake.Similar to other anthracyclines, it also induces histone eviction from chromatin.It belongs to the family of drugs called antitumor antibiotics.".
- Q1063862 label "Idarubicin".
- Q1063862 depiction Idarubicin.svg.