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- Q1034116 subject Q8617229.
- Q1034116 abstract "Nuclear cap-binding protein complex is a RNA-binding protein which binds to the 5' cap of pre-mRNA. The cap and nuclear cap-binding protein have many function in mRNA biogenesis including splicing, 3'-end formation by stabilizing the interaction of the 3'-end processing machinery, nuclear export and protection of the transcripts from nuclease degradation. When RNA is exported to the cytoplasm the nuclear cap-binding protein complex is replaced by cytoplasmic cap binding complex. The nuclear cap-binding complex is a functional heterodimer and composed of Cbc1/Cbc2 in yeast and CBC20/CBC80 in multicellular eukaryotes. Human nuclear cap-binding protein complex shows the large subunit, CBC80 consists of 757 amino acid residues. Its secondary structure contains approximately sixty percent of helical and one percent of beta sheet in the strand. The small subunit, CBC20 has 98 amino acid residues. Its secondary structure contains approximately twenty percent of helical and twenty-four percent of beta sheet in the strand. Human nuclear cap-binding protein complex plays important role in the maturation of pre-mRNA and uracil-rich small nuclear RNA.".
- Q1034116 arm "q".
- Q1034116 band "29".
- Q1034116 band "34.1".
- Q1034116 chromosome "3".
- Q1034116 chromosome "9".
- Q1034116 entrezgene "22916".
- Q1034116 entrezgene "4686".
- Q1034116 hgncid "7658".
- Q1034116 hgncid "7659".
- Q1034116 omim "605133".
- Q1034116 refseq "NM_002486".
- Q1034116 refseq "NM_007362".
- Q1034116 symbol "NCBP".
- Q1034116 symbol "NCBP1".
- Q1034116 symbol "NCBP2".
- Q1034116 thumbnail 1H6K.pdb.jpg?width=300.
- Q1034116 uniprot "P52298".
- Q1034116 wikiPageWikiLink Q135390.
- Q1034116 wikiPageWikiLink Q15712714.
- Q1034116 wikiPageWikiLink Q188928.
- Q1034116 wikiPageWikiLink Q238406.
- Q1034116 wikiPageWikiLink Q283399.
- Q1034116 wikiPageWikiLink Q283449.
- Q1034116 wikiPageWikiLink Q284390.
- Q1034116 wikiPageWikiLink Q284578.
- Q1034116 wikiPageWikiLink Q3928341.
- Q1034116 wikiPageWikiLink Q6589727.
- Q1034116 wikiPageWikiLink Q79899.
- Q1034116 wikiPageWikiLink Q8066.
- Q1034116 wikiPageWikiLink Q8617229.
- Q1034116 altsymbols "NCBP".
- Q1034116 arm "q".
- Q1034116 band "29".
- Q1034116 band "34.1".
- Q1034116 chromosome "3".
- Q1034116 chromosome "9".
- Q1034116 entrezgene "22916".
- Q1034116 entrezgene "4686".
- Q1034116 hgncid "7658".
- Q1034116 hgncid "7659".
- Q1034116 name "Nuclear cap binding protein subunit 2, 20kDa".
- Q1034116 name "nuclear cap-binding protein complex".
- Q1034116 omim "605133".
- Q1034116 refseq "NM_002486".
- Q1034116 refseq "NM_007362".
- Q1034116 symbol "NCBP1".
- Q1034116 symbol "NCBP2".
- Q1034116 uniprot "P52298".
- Q1034116 type Biomolecule.
- Q1034116 type Protein.
- Q1034116 type Thing.
- Q1034116 type Q206229.
- Q1034116 type Q8054.
- Q1034116 comment "Nuclear cap-binding protein complex is a RNA-binding protein which binds to the 5' cap of pre-mRNA. The cap and nuclear cap-binding protein have many function in mRNA biogenesis including splicing, 3'-end formation by stabilizing the interaction of the 3'-end processing machinery, nuclear export and protection of the transcripts from nuclease degradation. When RNA is exported to the cytoplasm the nuclear cap-binding protein complex is replaced by cytoplasmic cap binding complex.".
- Q1034116 label "Nuclear cap-binding protein complex".
- Q1034116 depiction 1H6K.pdb.jpg.
- Q1034116 name "Nuclear cap binding protein subunit 2, 20kDa".
- Q1034116 name "nuclear cap-binding protein complex".