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- mol.109.055970 author "Sotnikova TD, Caron MG, Gainetdinov RR".
- mol.109.055970 date "August 2009".
- mol.109.055970 doi "10.1124/mol.109.055970".
- mol.109.055970 isCitedBy Attention_deficit_hyperactivity_disorder.
- mol.109.055970 isCitedBy Trace_amine.
- mol.109.055970 issue "2".
- mol.109.055970 journal "Mol. Pharmacol.".
- mol.109.055970 pages "229–235".
- mol.109.055970 pages "229–35".
- mol.109.055970 pmc "2713119".
- mol.109.055970 pmid "19389919".
- mol.109.055970 quote "Although the functional role of trace amines in mammals remains largely enigmatic, it has been noted that trace amine levels can be altered in various human disorders, including schizophrenia, Parkinson's disease, attention deficit hyperactivity disorder , Tourette syndrome, and phenylketonuria . It was generally held that trace amines affect the monoamine system indirectly via interaction with plasma membrane transporters [such as plasma membrane dopamine transporter ] and vesicular storage . ...".
- mol.109.055970 quote "Furthermore, DAT-deficient mice provide a model to investigate the inhibitory actions of amphetamines on hyperactivity, the feature of amphetamines believed to be important for their therapeutic action in ADHD . It should be noted also that the best-established agonist of TAAR1, β-PEA, shared the ability of amphetamine to induce inhibition of dopamine-dependent hyperactivity of DAT-KO mice .".
- mol.109.055970 quote "Furthermore, if TAAR1 could be proven as a mediator of some of amphetamine's actions in vivo, the development of novel TAAR1-selective agonists and antagonists could provide a new approach for the treatment of amphetamine-related conditions such as addiction and/or disorders in which amphetamine is used therapeutically. In particular, because amphetamine has remained the most effective pharmacological treatment in ADHD for many years, a potential role of TAAR1 in the mechanism of the “paradoxical” effectiveness of amphetamine in this disorder should be explored.".
- mol.109.055970 title "Trace amine-associated receptors as emerging therapeutic targets".
- mol.109.055970 volume "76".