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- 02791072.2012.662112 author "Blum K, Werner T, Carnes S, Carnes P, Bowirrat A, Giordano J, Oscar-Berman M, Gold M".
- 02791072.2012.662112 date "March 2012".
- 02791072.2012.662112 doi "10.1080/02791072.2012.662112".
- 02791072.2012.662112 first1 "Kenneth".
- 02791072.2012.662112 first2 "Tonia".
- 02791072.2012.662112 first3 "Stefanie".
- 02791072.2012.662112 first4 "Patrick".
- 02791072.2012.662112 first5 "Abdalla".
- 02791072.2012.662112 first6 "John".
- 02791072.2012.662112 first8 "Mark".
- 02791072.2012.662112 isCitedBy Addiction.
- 02791072.2012.662112 isCitedBy Amphetamine.
- 02791072.2012.662112 isCitedBy Behavioral_addiction.
- 02791072.2012.662112 isCitedBy FOSB.
- 02791072.2012.662112 isCitedBy Mesolimbic_pathway.
- 02791072.2012.662112 isCitedBy Methamphetamine.
- 02791072.2012.662112 isCitedBy Nucleus_accumbens.
- 02791072.2012.662112 isCitedBy Opioid_addiction_and_dependence.
- 02791072.2012.662112 isCitedBy Sexual_addiction.
- 02791072.2012.662112 isCitedBy Sexual_intercourse.
- 02791072.2012.662112 isCitedBy Substance_dependence.
- 02791072.2012.662112 isCitedBy Substance_use_disorder.
- 02791072.2012.662112 issue "1".
- 02791072.2012.662112 journal "J. Psychoactive Drugs".
- 02791072.2012.662112 journal "Journal of Psychoactive Drugs".
- 02791072.2012.662112 last1 "Blum".
- 02791072.2012.662112 last2 "Werner".
- 02791072.2012.662112 last3 "Carnes".
- 02791072.2012.662112 last4 "Carnes".
- 02791072.2012.662112 last5 "Bowirrat".
- 02791072.2012.662112 last6 "Giordano".
- 02791072.2012.662112 last7 "Marlene-Oscar-Berman".
- 02791072.2012.662112 last7 "Oscar-Berman".
- 02791072.2012.662112 last8 "Gold".
- 02791072.2012.662112 pages "38–55".
- 02791072.2012.662112 pmc "4040958".
- 02791072.2012.662112 pmid "22641964".
- 02791072.2012.662112 quote "It has been found that deltaFosB gene in the is critical for reinforcing effects of sexual reward. Pitchers and colleagues reported that sexual experience was shown to cause DeltaFosB accumulation in several limbic brain regions including the NAc, medial pre-frontal cortex, , caudate, and putamen, but not the medial preoptic nucleus. ... these findings support a critical role for DeltaFosB expression in the NAc in the reinforcing effects of sexual behavior and sexual experience-induced facilitation of sexual performance. ... both drug addiction and sexual addiction represent pathological forms of neuroplasticity along with the emergence of aberrant behaviors involving a cascade of neurochemical changes mainly in the brain's rewarding circuitry.".
- 02791072.2012.662112 quote "It has been found that deltaFosB gene in the NAc is critical for reinforcing effects of sexual reward. Pitchers and colleagues reported that sexual experience was shown to cause DeltaFosB accumulation in several limbic brain regions including the NAc, medial pre-frontal cortex, VTA, caudate, and putamen, but not the medial preoptic nucleus. Next, the induction of c-Fos, a downstream target of DeltaFosB, was measured in sexually experienced and naive animals. The number of mating-induced c-Fos-IR cells was significantly decreased in sexually experienced animals compared to sexually naive controls. Finally, DeltaFosB levels and its activity in the NAc were manipulated using viral-mediated gene transfer to study its potential role in mediating sexual experience and experience-induced facilitation of sexual performance. Animals with DeltaFosB overexpression displayed enhanced facilitation of sexual performance with sexual experience relative to controls. In contrast, the expression of DeltaJunD, a dominant-negative binding partner of DeltaFosB, attenuated sexual experience-induced facilitation of sexual performance, and stunted long-term maintenance of facilitation compared to DeltaFosB overexpressing group. Together, these findings support a critical role for DeltaFosB expression in the NAc in the reinforcing effects of sexual behavior and sexual experience-induced facilitation of sexual performance. ... both drug addiction and sexual addiction represent pathological forms of neuroplasticity along with the emergence of aberrant behaviors involving a cascade of neurochemical changes mainly in the brain's rewarding circuitry.".
- 02791072.2012.662112 title "Sex, Drugs, and Rock 'N' Roll: Hypothesizing Common Mesolimbic Activation as a Function of Reward Gene Polymorphisms".
- 02791072.2012.662112 title "Sex, drugs, and rock 'n' roll: hypothesizing common mesolimbic activation as a function of reward gene polymorphisms".
- 02791072.2012.662112 vauthors "Blum K, Werner T, Carnes S, Carnes P, Bowirrat A, Giordano J, Oscar-Berman M, Gold M".
- 02791072.2012.662112 volume "44".
- 02791072.2012.662112 year "2012".