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- nature10600 accessdate "2016-02-06".
- nature10600 author "Baker, D.; Wijshake, T.; Tchkonia, T.; LeBrasseur, N.; Childs, B.; van de Sluis, B.; Kirkland, J.; van Deursen, J.".
- nature10600 author "Darren".
- nature10600 date "2011-11-10".
- nature10600 displayAuthors "etal".
- nature10600 doi "10.1038/nature10600".
- nature10600 isCitedBy P16.
- nature10600 isCitedBy Senescence.
- nature10600 isCitedBy Senolytic.
- nature10600 issue "7372".
- nature10600 journal "Nature".
- nature10600 pages "232–236".
- nature10600 pages "232–6".
- nature10600 pmc "3468323".
- nature10600 pmid "22048312".
- nature10600 quote "(Here we show that in the BubR1 progeroid mouse background, INK-ATTAC removes p16Ink4a-positive senescent cells upon drug treatment. In tissues—such as adipose tissue, skeletal muscle and eye—in which p16Ink4a contributes to the acquisition of age-related pathologies, life-long removal of p16Ink4a-expressing cells delayed onset of these phenotypes. Furthermore, late-life clearance attenuated progression of already established age-related disorders. These data indicate that cellular senescence is causally implicated in generating age-related phenotypes and that removal of senescent cells can prevent or delay tissue dysfunction and extend healthspan.)".
- nature10600 title "Clearance of p16Ink4a-Positive Senescent Cells Delays Aging-Associated Disorders".
- nature10600 title "Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders".
- nature10600 url nature10600.
- nature10600 vauthors "Baker DJ, Wijshake T, Tchkonia T, LeBrasseur NK, Childs BG, van de Sluis B, Kirkland JL, van Deursen JM".
- nature10600 volume "479".
- nature10600 year "2011".