Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/WAY-267,464> ?p ?o }
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- WAY-267,464 abstract "WAY-267,464 is a potent, selective, non-peptide agonist for the oxytocin receptor, with negligible affinity for the vasopressin receptors. Contradictorily however, though originally described as selective for the oxytocin receptor and lacking affinity for the vasopressin receptors, it has since been reported to also act as a potent vasopressin V1A receptor antagonist (in contrast to oxytocin, which is a weak agonist of the V1A receptor). WAY-267,464 has been shown to cross the blood-brain-barrier to a significantly greater extent than exogenously applied oxytocin, and in animal tests produces centrally-mediated oxytocinergic actions such as anxiolytic effects, but with no antidepressant effect evident. It was developed by a team at Ferring Pharmaceuticals.WAY-267,464 is or was under investigation for the potential clinical treatment of anxiety disorders by Wyeth.[1]".
- WAY-267,464 atcPrefix "none".
- WAY-267,464 casNumber "847375-16-0".
- WAY-267,464 iupacName "4-(3,5-Dihydroxybenzyl)-N-(2-methyl-4-[(1-methyl-4,10-dihydropyrazolo[3,4-b][1,5]benzodiazepin-5(1H)-yl)carbonyl]benzyl)piperazine-1-carboxamide".
- WAY-267,464 pubchem "9938214".
- WAY-267,464 thumbnail WAY-267,464.svg?width=300.
- WAY-267,464 wikiPageExternalLink 800029344.
- WAY-267,464 wikiPageID "23858376".
- WAY-267,464 wikiPageLength "4817".
- WAY-267,464 wikiPageOutDegree "23".
- WAY-267,464 wikiPageRevisionID "699645850".
- WAY-267,464 wikiPageWikiLink Agonist.
- WAY-267,464 wikiPageWikiLink Antidepressant.
- WAY-267,464 wikiPageWikiLink Anxiety_disorder.
- WAY-267,464 wikiPageWikiLink Anxiolytic.
- WAY-267,464 wikiPageWikiLink Arginine_vasopressin_receptor_1A.
- WAY-267,464 wikiPageWikiLink Blood–brain_barrier.
- WAY-267,464 wikiPageWikiLink Category:Amides.
- WAY-267,464 wikiPageWikiLink Category:Anxiolytics.
- WAY-267,464 wikiPageWikiLink Category:Benzodiazepines.
- WAY-267,464 wikiPageWikiLink Category:Oxytocin_receptor_agonists.
- WAY-267,464 wikiPageWikiLink Category:Piperazines.
- WAY-267,464 wikiPageWikiLink Category:Resorcinols.
- WAY-267,464 wikiPageWikiLink Category:Vasopressin_receptor_antagonists.
- WAY-267,464 wikiPageWikiLink Ferring_Pharmaceuticals.
- WAY-267,464 wikiPageWikiLink Ligand_(biochemistry).
- WAY-267,464 wikiPageWikiLink Oxytocin.
- WAY-267,464 wikiPageWikiLink Oxytocin_receptor.
- WAY-267,464 wikiPageWikiLink Receptor_antagonist.
- WAY-267,464 wikiPageWikiLink Small_molecule.
- WAY-267,464 wikiPageWikiLink TC_OT_39.
- WAY-267,464 wikiPageWikiLink Uterotonic.
- WAY-267,464 wikiPageWikiLink Vasopressin_receptor.
- WAY-267,464 wikiPageWikiLink Wyeth.
- WAY-267,464 wikiPageWikiLinkText "WAY-267,464".
- WAY-267,464 atcPrefix "none".
- WAY-267,464 c "32".
- WAY-267,464 casNumber "847375".
- WAY-267,464 chemspiderid "31047382".
- WAY-267,464 h "35".
- WAY-267,464 inchi "1".
- WAY-267,464 inchikey "HWPGRFRXZNLZEX-UHFFFAOYAC".
- WAY-267,464 iupacName "4".
- WAY-267,464 legalStatus "Uncontrolled".
- WAY-267,464 molecularWeight "581.677".
- WAY-267,464 n "7".
- WAY-267,464 o "4".
- WAY-267,464 pubchem "9938214".
- WAY-267,464 routesOfAdministration "?".
- WAY-267,464 smiles "OC1=CC=CC=C1".
- WAY-267,464 stdinchi "1".
- WAY-267,464 stdinchikey "HWPGRFRXZNLZEX-UHFFFAOYSA-N".
- WAY-267,464 verifiedfields "changed".
- WAY-267,464 verifiedrevid "451221682".
- WAY-267,464 watchedfields "changed".
- WAY-267,464 width "275".
- WAY-267,464 wikiPageUsesTemplate Template:Cascite.
- WAY-267,464 wikiPageUsesTemplate Template:Chemspidercite.
- WAY-267,464 wikiPageUsesTemplate Template:Drugbox.
- WAY-267,464 wikiPageUsesTemplate Template:Genito-urinary-drug-stub.
- WAY-267,464 wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- WAY-267,464 wikiPageUsesTemplate Template:Neuropeptidergics.
- WAY-267,464 wikiPageUsesTemplate Template:Reflist.
- WAY-267,464 wikiPageUsesTemplate Template:Stdinchicite.
- WAY-267,464 subject Category:Amides.
- WAY-267,464 subject Category:Anxiolytics.
- WAY-267,464 subject Category:Benzodiazepines.
- WAY-267,464 subject Category:Oxytocin_receptor_agonists.
- WAY-267,464 subject Category:Piperazines.
- WAY-267,464 subject Category:Resorcinols.
- WAY-267,464 subject Category:Vasopressin_receptor_antagonists.
- WAY-267,464 hypernym Agonist.
- WAY-267,464 type ChemicalSubstance.
- WAY-267,464 type Drug.
- WAY-267,464 type Group.
- WAY-267,464 type Amide.
- WAY-267,464 type Anticonvulsant.
- WAY-267,464 type Benzenediol.
- WAY-267,464 type Benzodiazepine.
- WAY-267,464 type Chemical.
- WAY-267,464 type Drug.
- WAY-267,464 type Group.
- WAY-267,464 type Heterocycle.
- WAY-267,464 type ChemicalObject.
- WAY-267,464 type Thing.
- WAY-267,464 type Q8386.
- WAY-267,464 comment "WAY-267,464 is a potent, selective, non-peptide agonist for the oxytocin receptor, with negligible affinity for the vasopressin receptors. Contradictorily however, though originally described as selective for the oxytocin receptor and lacking affinity for the vasopressin receptors, it has since been reported to also act as a potent vasopressin V1A receptor antagonist (in contrast to oxytocin, which is a weak agonist of the V1A receptor).".
- WAY-267,464 label "WAY-267,464".
- WAY-267,464 sameAs Q7946884.
- WAY-267,464 sameAs m.076zt85.
- WAY-267,464 sameAs WAY-267,464.
- WAY-267,464 sameAs WAY-267,464.
- WAY-267,464 sameAs Q7946884.
- WAY-267,464 wasDerivedFrom WAY-267,464?oldid=699645850.
- WAY-267,464 depiction WAY-267,464.svg.
- WAY-267,464 isPrimaryTopicOf WAY-267,464.