Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/WAY-181,187> ?p ?o }
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- WAY-181,187 abstract "WAY-181,187 is a high affinity and selective 5-HT6 receptor full agonist. It induces robust increases in extracellular GABA levels in the frontal cortex, hippocampus, striatum, and amygdala of rats without affecting concentrations in the nucleus accumbens or thalamus, and has modest to no effects on norepinephrine, serotonin, dopamine, or glutamate levels in these areas. WAY-181,187 has demonstrated preclinical efficacy in rodent models of depression, anxiety, and notably obsessive-compulsive disorder, though it has also been shown to impair cognition and memory.".
- WAY-181,187 atcPrefix "none".
- WAY-181,187 casNumber "?".
- WAY-181,187 iupacName "2-(1-{6-chloroimidazo[2,1-b][1,3]thiazole-5-sulfonyl}-1H-indol-3-yl)ethan-1-amine".
- WAY-181,187 pubchem "10150497".
- WAY-181,187 thumbnail WAY-181,187.svg?width=300.
- WAY-181,187 wikiPageID "26753686".
- WAY-181,187 wikiPageLength "4069".
- WAY-181,187 wikiPageOutDegree "23".
- WAY-181,187 wikiPageRevisionID "679113534".
- WAY-181,187 wikiPageWikiLink 5-HT6_receptor.
- WAY-181,187 wikiPageWikiLink Agonist.
- WAY-181,187 wikiPageWikiLink Amygdala.
- WAY-181,187 wikiPageWikiLink Anxiety.
- WAY-181,187 wikiPageWikiLink Binding_selectivity.
- WAY-181,187 wikiPageWikiLink Category:Serotonin_receptor_agonists.
- WAY-181,187 wikiPageWikiLink Cognition.
- WAY-181,187 wikiPageWikiLink Dopamine.
- WAY-181,187 wikiPageWikiLink Extracellular.
- WAY-181,187 wikiPageWikiLink Frontal_lobe.
- WAY-181,187 wikiPageWikiLink Gamma-Aminobutyric_acid.
- WAY-181,187 wikiPageWikiLink Glutamic_acid.
- WAY-181,187 wikiPageWikiLink Hippocampus.
- WAY-181,187 wikiPageWikiLink Ligand_(biochemistry).
- WAY-181,187 wikiPageWikiLink Major_depressive_disorder.
- WAY-181,187 wikiPageWikiLink Memory.
- WAY-181,187 wikiPageWikiLink Norepinephrine.
- WAY-181,187 wikiPageWikiLink Nucleus_accumbens.
- WAY-181,187 wikiPageWikiLink Obsessive–compulsive_disorder.
- WAY-181,187 wikiPageWikiLink Serotonin.
- WAY-181,187 wikiPageWikiLink Striatum.
- WAY-181,187 wikiPageWikiLink Thalamus.
- WAY-181,187 wikiPageWikiLink WAY-208,466.
- WAY-181,187 wikiPageWikiLinkText "WAY-181,187".
- WAY-181,187 atcPrefix "none".
- WAY-181,187 c "15".
- WAY-181,187 casNumber "?".
- WAY-181,187 chembl "392760".
- WAY-181,187 chemspiderid "8326005".
- WAY-181,187 cl "1".
- WAY-181,187 h "13".
- WAY-181,187 inchi "1".
- WAY-181,187 inchikey "RYBOXBBYCVOYNO-UHFFFAOYAQ".
- WAY-181,187 iupacName "2".
- WAY-181,187 iupharLigand "3240".
- WAY-181,187 molecularWeight "380.872".
- WAY-181,187 n "4".
- WAY-181,187 o "2".
- WAY-181,187 pubchem "10150497".
- WAY-181,187 s "2".
- WAY-181,187 smiles "NCCc1cnSc1cnc2sccn12".
- WAY-181,187 stdinchi "1".
- WAY-181,187 stdinchikey "RYBOXBBYCVOYNO-UHFFFAOYSA-N".
- WAY-181,187 width "200".
- WAY-181,187 wikiPageUsesTemplate Template:Antidepressants.
- WAY-181,187 wikiPageUsesTemplate Template:Anxiolytics.
- WAY-181,187 wikiPageUsesTemplate Template:Drugbox.
- WAY-181,187 wikiPageUsesTemplate Template:Ebicite.
- WAY-181,187 wikiPageUsesTemplate Template:Obsessive–compulsive_disorder.
- WAY-181,187 wikiPageUsesTemplate Template:Reflist.
- WAY-181,187 wikiPageUsesTemplate Template:Serotonergics.
- WAY-181,187 subject Category:Serotonin_receptor_agonists.
- WAY-181,187 hypernym Affinity.
- WAY-181,187 type ChemicalSubstance.
- WAY-181,187 type Drug.
- WAY-181,187 type Agonist.
- WAY-181,187 type Chemical.
- WAY-181,187 type Drug.
- WAY-181,187 type Redirect.
- WAY-181,187 type ChemicalObject.
- WAY-181,187 type Thing.
- WAY-181,187 type Q8386.
- WAY-181,187 comment "WAY-181,187 is a high affinity and selective 5-HT6 receptor full agonist. It induces robust increases in extracellular GABA levels in the frontal cortex, hippocampus, striatum, and amygdala of rats without affecting concentrations in the nucleus accumbens or thalamus, and has modest to no effects on norepinephrine, serotonin, dopamine, or glutamate levels in these areas.".
- WAY-181,187 label "WAY-181,187".
- WAY-181,187 sameAs Q487463.
- WAY-181,187 sameAs m.0bmk0s8.
- WAY-181,187 sameAs WAY-181,187.
- WAY-181,187 sameAs WAY-181,187.
- WAY-181,187 sameAs Q487463.
- WAY-181,187 wasDerivedFrom WAY-181,187?oldid=679113534.
- WAY-181,187 depiction WAY-181,187.svg.
- WAY-181,187 isPrimaryTopicOf WAY-181,187.