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- Vesicular-tubular_cluster abstract "The vesicular-tubular cluster (VTC), also referred to as the ER-Golgi intermediate compartment (or ERGIC), is an organelle in eukaryotic cells. This compartment mediates trafficking between the endoplasmic reticulum and Golgi complex, facilitating the sorting of cargo. First discovered in 1984, the compartment was first defined as the location within the cell of the mannose-binding membrane lectin called ERGIC-53.In mammalian organisms, COPII vesicles that have budded from exit sites in the endoplasmic reticulum lose their coats and fuse to form the vesicular-tubular cluster (VTC). Retrieval (or retrograde) transport in COPI vesicles returns many of the lost ER resident proteins back to the endoplasmic reticulum. Forward (or anterograde) transport moves the VTC contents to the cis-Golgi network, the receiving face of the Golgi complex. This process is thought to occur by one of two processes. One is known as cisternal maturation where the VTC simply matures into the cis-Golgi network. In another, COPI vesicular transport moves VTC material to the receiving face of the Golgi apparatus through movement of the VTC along microtubules. A fuller explanation of the two processes is described (see Golgi complex). Evidence exists for both processes and it may be that both occur simultaneously in cells.".
- Vesicular-tubular_cluster wikiPageID "6915948".
- Vesicular-tubular_cluster wikiPageLength "2431".
- Vesicular-tubular_cluster wikiPageOutDegree "11".
- Vesicular-tubular_cluster wikiPageRevisionID "626373434".
- Vesicular-tubular_cluster wikiPageWikiLink COPI.
- Vesicular-tubular_cluster wikiPageWikiLink COPII.
- Vesicular-tubular_cluster wikiPageWikiLink Category:Organelles.
- Vesicular-tubular_cluster wikiPageWikiLink Endoplasmic_reticulum.
- Vesicular-tubular_cluster wikiPageWikiLink Golgi_apparatus.
- Vesicular-tubular_cluster wikiPageWikiLink LMAN1.
- Vesicular-tubular_cluster wikiPageWikiLink Lectin.
- Vesicular-tubular_cluster wikiPageWikiLink Mammal.
- Vesicular-tubular_cluster wikiPageWikiLink Organelle.
- Vesicular-tubular_cluster wikiPageWikiLinkText "ERGIC".
- Vesicular-tubular_cluster wikiPageWikiLinkText "Vesicular-tubular cluster".
- Vesicular-tubular_cluster wikiPageWikiLinkText "vesicular-tubular cluster".
- Vesicular-tubular_cluster wikiPageUsesTemplate Template:Reflist.
- Vesicular-tubular_cluster subject Category:Organelles.
- Vesicular-tubular_cluster hypernym Organelle.
- Vesicular-tubular_cluster type Protein.
- Vesicular-tubular_cluster comment "The vesicular-tubular cluster (VTC), also referred to as the ER-Golgi intermediate compartment (or ERGIC), is an organelle in eukaryotic cells. This compartment mediates trafficking between the endoplasmic reticulum and Golgi complex, facilitating the sorting of cargo.".
- Vesicular-tubular_cluster label "Vesicular-tubular cluster".
- Vesicular-tubular_cluster sameAs Q7923223.
- Vesicular-tubular_cluster sameAs VTCs.
- Vesicular-tubular_cluster sameAs ERGIC.
- Vesicular-tubular_cluster sameAs m.0gwx2k.
- Vesicular-tubular_cluster sameAs Q7923223.
- Vesicular-tubular_cluster wasDerivedFrom Vesicular-tubular_cluster?oldid=626373434.
- Vesicular-tubular_cluster isPrimaryTopicOf Vesicular-tubular_cluster.