Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Ubiquitin_ligase> ?p ?o }
- Ubiquitin_ligase abstract "A ubiquitin ligase (also called an E3 ubiquitin ligase) is a protein that recruits an E2 ubiquitin-conjugating enzyme that has been loaded with ubiquitin, recognizes a protein substrate, and assists or directly catalyzes the transfer of ubiquitin from the E2 to the protein substrate. The ubiquitin is attached to a lysine on the target protein by an isopeptide bond. E3 ligases interact with both the target protein and the E2 enzyme, and so impart substrate specificity to the E2. Commonly, E3s polyubiquitinate their substrate with Lys48-linked chains of ubiquitin, targeting the substrate for destruction by the proteasome. However, many other types of linkages are possible and alter a protein's activity, interactions, or localization. Ubiquitination by E3 ligases regulates diverse areas such as cell trafficking, DNA repair, and signaling and is of profound importance in cell biology. E3 ligases are also key players in cell cycle control, mediating the degradation of cyclins, as well as cyclin dependent kinase inhibitor proteins. The human genome encodes over 600 putative E3 ligases, allowing for tremendous diversity in substrates.".
- Ubiquitin_ligase ecNumber "6.3.2.19".
- Ubiquitin_ligase thumbnail 4a4c.png?width=300.
- Ubiquitin_ligase wikiPageExternalLink quips?story=LordCBL.
- Ubiquitin_ligase wikiPageExternalLink www.pdbe.org.
- Ubiquitin_ligase wikiPageID "622571".
- Ubiquitin_ligase wikiPageLength "15849".
- Ubiquitin_ligase wikiPageOutDegree "110".
- Ubiquitin_ligase wikiPageRevisionID "704005320".
- Ubiquitin_ligase wikiPageWikiLink Adenosine_monophosphate.
- Ubiquitin_ligase wikiPageWikiLink Adenosine_triphosphate.
- Ubiquitin_ligase wikiPageWikiLink Anaphase-promoting_complex.
- Ubiquitin_ligase wikiPageWikiLink BRCA1.
- Ubiquitin_ligase wikiPageWikiLink Biotransformation.
- Ubiquitin_ligase wikiPageWikiLink CBLL1.
- Ubiquitin_ligase wikiPageWikiLink CBX4.
- Ubiquitin_ligase wikiPageWikiLink CUL5.
- Ubiquitin_ligase wikiPageWikiLink Catalysis.
- Ubiquitin_ligase wikiPageWikiLink Category:EC_6.3.
- Ubiquitin_ligase wikiPageWikiLink Category:Posttranslational_modification.
- Ubiquitin_ligase wikiPageWikiLink Chemical_reaction.
- Ubiquitin_ligase wikiPageWikiLink Cullin.
- Ubiquitin_ligase wikiPageWikiLink Cyclin.
- Ubiquitin_ligase wikiPageWikiLink Cyclin-dependent_kinase_inhibitor_protein.
- Ubiquitin_ligase wikiPageWikiLink Cysteine.
- Ubiquitin_ligase wikiPageWikiLink Endocytosis.
- Ubiquitin_ligase wikiPageWikiLink Endoplasmic-reticulum-associated_protein_degradation.
- Ubiquitin_ligase wikiPageWikiLink Enzyme.
- Ubiquitin_ligase wikiPageWikiLink Epidermal_growth_factor_receptor.
- Ubiquitin_ligase wikiPageWikiLink HACE1.
- Ubiquitin_ligase wikiPageWikiLink HECTD1.
- Ubiquitin_ligase wikiPageWikiLink HECTD2.
- Ubiquitin_ligase wikiPageWikiLink HECTD3.
- Ubiquitin_ligase wikiPageWikiLink HECT_domain.
- Ubiquitin_ligase wikiPageWikiLink HECW1.
- Ubiquitin_ligase wikiPageWikiLink HECW2.
- Ubiquitin_ligase wikiPageWikiLink HERC1.
- Ubiquitin_ligase wikiPageWikiLink HERC2.
- Ubiquitin_ligase wikiPageWikiLink HERC3.
- Ubiquitin_ligase wikiPageWikiLink HERC4.
- Ubiquitin_ligase wikiPageWikiLink HUWE1.
- Ubiquitin_ligase wikiPageWikiLink Huntingtons_disease.
- Ubiquitin_ligase wikiPageWikiLink ITCH.
- Ubiquitin_ligase wikiPageWikiLink Isopeptide_bond.
- Ubiquitin_ligase wikiPageWikiLink Ligase.
- Ubiquitin_ligase wikiPageWikiLink Liver_cancer.
- Ubiquitin_ligase wikiPageWikiLink Lysine.
- Ubiquitin_ligase wikiPageWikiLink Mdm2.
- Ubiquitin_ligase wikiPageWikiLink Metabolism.
- Ubiquitin_ligase wikiPageWikiLink Multiprotein_complex.
- Ubiquitin_ligase wikiPageWikiLink NEDD4.
- Ubiquitin_ligase wikiPageWikiLink NEDD4L.
- Ubiquitin_ligase wikiPageWikiLink P21.
- Ubiquitin_ligase wikiPageWikiLink P53.
- Ubiquitin_ligase wikiPageWikiLink PIAS1.
- Ubiquitin_ligase wikiPageWikiLink PIAS3.
- Ubiquitin_ligase wikiPageWikiLink PIAS4.
- Ubiquitin_ligase wikiPageWikiLink PPIL2.
- Ubiquitin_ligase wikiPageWikiLink PRPF19.
- Ubiquitin_ligase wikiPageWikiLink Parkinsons_disease.
- Ubiquitin_ligase wikiPageWikiLink Product_(chemistry).
- Ubiquitin_ligase wikiPageWikiLink Proteasome.
- Ubiquitin_ligase wikiPageWikiLink Protein.
- Ubiquitin_ligase wikiPageWikiLink Protein_inhibitor_of_activated_STAT2.
- Ubiquitin_ligase wikiPageWikiLink Pyrophosphate.
- Ubiquitin_ligase wikiPageWikiLink RANBP2.
- Ubiquitin_ligase wikiPageWikiLink RBX1.
- Ubiquitin_ligase wikiPageWikiLink RING_finger_domain.
- Ubiquitin_ligase wikiPageWikiLink RNF4.
- Ubiquitin_ligase wikiPageWikiLink Renal_cell_carcinoma.
- Ubiquitin_ligase wikiPageWikiLink SCF_complex.
- Ubiquitin_ligase wikiPageWikiLink SH2_domain.
- Ubiquitin_ligase wikiPageWikiLink SMURF1.
- Ubiquitin_ligase wikiPageWikiLink SMURF2.
- Ubiquitin_ligase wikiPageWikiLink STUB1.
- Ubiquitin_ligase wikiPageWikiLink Sic1.
- Ubiquitin_ligase wikiPageWikiLink Skp1.
- Ubiquitin_ligase wikiPageWikiLink Sp1_transcription_factor.
- Ubiquitin_ligase wikiPageWikiLink Stomach_cancer.
- Ubiquitin_ligase wikiPageWikiLink Substrate_(chemistry).
- Ubiquitin_ligase wikiPageWikiLink Suppressor_of_cytokine_signalling.
- Ubiquitin_ligase wikiPageWikiLink TOPORS.
- Ubiquitin_ligase wikiPageWikiLink TRIP12.
- Ubiquitin_ligase wikiPageWikiLink Thioester.
- Ubiquitin_ligase wikiPageWikiLink UBE3A.
- Ubiquitin_ligase wikiPageWikiLink UBE3B.
- Ubiquitin_ligase wikiPageWikiLink UBE3C.
- Ubiquitin_ligase wikiPageWikiLink UBE4A.
- Ubiquitin_ligase wikiPageWikiLink UBE4B.
- Ubiquitin_ligase wikiPageWikiLink UBOX5.
- Ubiquitin_ligase wikiPageWikiLink UBR5.
- Ubiquitin_ligase wikiPageWikiLink Ubiquitin.
- Ubiquitin_ligase wikiPageWikiLink Ubiquitin-activating_enzyme.
- Ubiquitin_ligase wikiPageWikiLink Ubiquitin-conjugating_enzyme.
- Ubiquitin_ligase wikiPageWikiLink Von_Hippel–Lindau_tumor_suppressor.
- Ubiquitin_ligase wikiPageWikiLink WWP1.
- Ubiquitin_ligase wikiPageWikiLink WWP2.
- Ubiquitin_ligase wikiPageWikiLink File:Ubiquitin_Lysines.png.
- Ubiquitin_ligase wikiPageWikiLink File:Ubiquitylation.png.
- Ubiquitin_ligase wikiPageWikiLinkText "E2/E3 ligase pair".