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- Treponema_pallidum_particle_agglutination_assay abstract "The Treponema pallidum particle agglutination assay (also called TPPA test) is an indirect agglutination assay used for detection and titration of antibodies against the causative agent of syphilis, Treponema pallidum subspecies pallidum.In the test, gelatin particles are sensitized with T. pallidum antigen. Patient serum is mixed with the reagent containing the sensitized gelatin particles. The particles aggregate to form clumps when the patient serum is positive for syphilis. In other words, the patient's serum contains antibodies to T. pallidum. A negative test shows no clumping of gelatin particles. This is a type of specific treponemal test for syphilis. A similar specific treponemal test for syphilis is the Treponema pallidum hemagglutination assay or TPHA. TPHA is an indirect hemagglutination assay used for the detection and titration of antibodies against the causative agent of syphilis, Treponema pallidum subspecies pallidum.In the test, red blood cells (erythrocytes) are sensitized with antigens from T. pallidum pallidum. The cells then aggregate on the surface of a test dish if exposed to the serum of a patient with syphilis. It is used as a confirmatory test for syphilis infection. A negative test result shows a tight button or spot of red blood cells on the surface of the test dish. Often a plastic test plate containing many small \"wells\" is used as the test dish so that many patients may be tested at the same time but their results can be kept separate from each other. Please note the image of the wells on the test plate and the positive and negative test results look different.[2]For primary syphilis, TPPA has a sensitivity of 85% to 100%, and a specificity of 98% to 100%. In secondary and late-latent syphilis, TPPA has a sensitivity of 98% to 100%.Antibodies against other treponemal organisms, such as the T. pallidum subspecies endemicum, pertenue, or carateum, can cause false positive results. A variety of methods exist to adsorb these antibodies from the test sample before hemagglutination.".
- Treponema_pallidum_particle_agglutination_assay thumbnail TPHA_test_on_microplate_wells.jpg?width=300.
- Treponema_pallidum_particle_agglutination_assay wikiPageID "32090767".
- Treponema_pallidum_particle_agglutination_assay wikiPageLength "3304".
- Treponema_pallidum_particle_agglutination_assay wikiPageOutDegree "10".
- Treponema_pallidum_particle_agglutination_assay wikiPageRevisionID "671138307".
- Treponema_pallidum_particle_agglutination_assay wikiPageWikiLink Category:Sexually_transmitted_diseases_and_infections.
- Treponema_pallidum_particle_agglutination_assay wikiPageWikiLink Category:Syphilis.
- Treponema_pallidum_particle_agglutination_assay wikiPageWikiLink Red_blood_cell.
- Treponema_pallidum_particle_agglutination_assay wikiPageWikiLink Sensitivity_and_specificity.
- Treponema_pallidum_particle_agglutination_assay wikiPageWikiLink Syphilis.
- Treponema_pallidum_particle_agglutination_assay wikiPageWikiLink Treponema_pallidum.
- Treponema_pallidum_particle_agglutination_assay wikiPageWikiLink File:TPHA_test_on_microplate_wells.jpg.
- Treponema_pallidum_particle_agglutination_assay wikiPageWikiLinkText "Treponema pallidum particle agglutination assay".
- Treponema_pallidum_particle_agglutination_assay wikiPageUsesTemplate Template:Reflist.
- Treponema_pallidum_particle_agglutination_assay subject Category:Sexually_transmitted_diseases_and_infections.
- Treponema_pallidum_particle_agglutination_assay subject Category:Syphilis.
- Treponema_pallidum_particle_agglutination_assay hypernym Assay.
- Treponema_pallidum_particle_agglutination_assay type Disorder.
- Treponema_pallidum_particle_agglutination_assay comment "The Treponema pallidum particle agglutination assay (also called TPPA test) is an indirect agglutination assay used for detection and titration of antibodies against the causative agent of syphilis, Treponema pallidum subspecies pallidum.In the test, gelatin particles are sensitized with T. pallidum antigen. Patient serum is mixed with the reagent containing the sensitized gelatin particles. The particles aggregate to form clumps when the patient serum is positive for syphilis.".
- Treponema_pallidum_particle_agglutination_assay label "Treponema pallidum particle agglutination assay".
- Treponema_pallidum_particle_agglutination_assay sameAs Q461041.
- Treponema_pallidum_particle_agglutination_assay sameAs تراص_جسيمات_الولبية_الشاحبة.
- Treponema_pallidum_particle_agglutination_assay sameAs TPHA.
- Treponema_pallidum_particle_agglutination_assay sameAs سنجش_لختگی_ذرات_تارپیچ_پالیدیوم.
- Treponema_pallidum_particle_agglutination_assay sameAs TPHA.
- Treponema_pallidum_particle_agglutination_assay sameAs m.03bzx83.
- Treponema_pallidum_particle_agglutination_assay sameAs Q461041.
- Treponema_pallidum_particle_agglutination_assay wasDerivedFrom Treponema_pallidum_particle_agglutination_assay?oldid=671138307.
- Treponema_pallidum_particle_agglutination_assay depiction TPHA_test_on_microplate_wells.jpg.
- Treponema_pallidum_particle_agglutination_assay isPrimaryTopicOf Treponema_pallidum_particle_agglutination_assay.