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- Toxin_and_Toxin-Target_Database abstract "The Toxin and Toxin-Target Database (T3DB), also known as the Toxic Exposome Database, is a freely accessible online database of common substances that are toxic to humans, along with their protein, DNA or organ targets. The database currently houses nearly 3,700 toxic compounds or poisons described by nearly 42,000 synonyms. This list includes various groups of toxins, including common pollutants, pesticides, drugs, food toxins, household and industrial/workplace toxins, cigarette toxins, and uremic toxins. These toxic substances are linked to 2,086 corresponding protein/DNA target records. In total there are 42,433 toxic substance-toxin target associations. Each toxic compound record (ToxCard) in T3DB contains nearly 100 data fields and holds information such as chemical properties and descriptors, mechanisms of action, toxicity or lethal dose values, molecular and cellular interactions, medical (symptom and treatment) information (Fig. 1-3), NMR an MS spectra, and up- and down-regulated genes. This information has been extracted from over 18,000 sources, which include other databases, government documents, books, and scientific literature.The primary focus of the T3DB is on providing mechanisms of toxicity and identifying target proteins for common toxic substances. While a number of other toxic compound databases do exist, their emphasis is on covering large numbers of chemical compounds that are almost never seen outside a chemical laboratory. T3DB attempts to capture data on only those toxic substances that are abundant or in widespread use and have been detected or measured in humans. T3DB is fully searchable and supports extensive text, sequence, chemical structure, relational query and spectral searches. It is both modelled after and closely linked to the Human Metabolome Database (HMDB) and DrugBank. Potential applications of T3DB include metabolomics and environmental exposure studies, toxic compound metabolism prediction, toxin/drug interaction prediction, and general toxic substance awareness.".
- Toxin_and_Toxin-Target_Database thumbnail T3db-banner.jpg?width=300.
- Toxin_and_Toxin-Target_Database wikiPageExternalLink www.metabolomicscentre.ca.
- Toxin_and_Toxin-Target_Database wikiPageExternalLink www.t3db.ca.
- Toxin_and_Toxin-Target_Database wikiPageExternalLink downloads.
- Toxin_and_Toxin-Target_Database wikiPageExternalLink sources.
- Toxin_and_Toxin-Target_Database wikiPageExternalLink databases.
- Toxin_and_Toxin-Target_Database wikiPageExternalLink www.wishartlab.com.
- Toxin_and_Toxin-Target_Database wikiPageID "34344052".
- Toxin_and_Toxin-Target_Database wikiPageLength "4895".
- Toxin_and_Toxin-Target_Database wikiPageOutDegree "37".
- Toxin_and_Toxin-Target_Database wikiPageRevisionID "673382315".
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Biological_target.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Category:Biological_databases.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Category:Chemical_databases.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Category:Metabolomic_databases.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Chemical_structure.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink DNA.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Drug.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink DrugBank.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Exposome.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Human_Metabolome_Database.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink KEGG.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Lethal_dose.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink List_of_biological_databases.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink List_of_extremely_hazardous_substances.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Mass_spectrum.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Mechanism_of_action.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Metabolism.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Metabolomics.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Nuclear_magnetic_resonance_spectroscopy.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Pesticide.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Poison.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Pollutant.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Protein.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Regulation_of_gene_expression.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Relational_database.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Small_Molecule_Pathway_Database.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Toxicant.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Toxicity.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Toxin.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink Uremic_toxin.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink File:T3DB-arsenic-toxicity.png.
- Toxin_and_Toxin-Target_Database wikiPageWikiLink File:T3db-banner.jpg.
- Toxin_and_Toxin-Target_Database wikiPageWikiLinkText "Toxin and Toxin-Target Database".
- Toxin_and_Toxin-Target_Database center "University of Alberta and The Metabolomics Innovation Centre".
- Toxin_and_Toxin-Target_Database curation "Manually curated".
- Toxin_and_Toxin-Target_Database description "Toxin and toxin target database".
- Toxin_and_Toxin-Target_Database download downloads.
- Toxin_and_Toxin-Target_Database frequency "-1.262304E8".
- Toxin_and_Toxin-Target_Database laboratory www.wishartlab.com.
- Toxin_and_Toxin-Target_Database logo "300".
- Toxin_and_Toxin-Target_Database pmid "T3DB: the toxic exposome database.".
- Toxin_and_Toxin-Target_Database released "2009".
- Toxin_and_Toxin-Target_Database scope "Small molecule poisons, toxic compounds and toxins, chemical structures, toxic compound descriptions, chemical taxonomy, toxin targets and transporters, target protein sequences, mechanisms of action, lethal doses, chemical properties, nomenclature, synonyms, NMR spectra, MS spectra, gene regulation, concentrations".
- Toxin_and_Toxin-Target_Database url www.t3db.ca.
- Toxin_and_Toxin-Target_Database wikiPageUsesTemplate Template:Infobox_biodatabase.
- Toxin_and_Toxin-Target_Database wikiPageUsesTemplate Template:One_source.
- Toxin_and_Toxin-Target_Database wikiPageUsesTemplate Template:Reflist.
- Toxin_and_Toxin-Target_Database description "Toxin and toxin target database".
- Toxin_and_Toxin-Target_Database subject Category:Biological_databases.
- Toxin_and_Toxin-Target_Database subject Category:Chemical_databases.
- Toxin_and_Toxin-Target_Database subject Category:Metabolomic_databases.
- Toxin_and_Toxin-Target_Database type BiologicalDatabase.
- Toxin_and_Toxin-Target_Database type Database.
- Toxin_and_Toxin-Target_Database type Work.
- Toxin_and_Toxin-Target_Database type Cheminformatic.
- Toxin_and_Toxin-Target_Database type CreativeWork.
- Toxin_and_Toxin-Target_Database type InformationObject.
- Toxin_and_Toxin-Target_Database type Thing.
- Toxin_and_Toxin-Target_Database type Q386724.
- Toxin_and_Toxin-Target_Database comment "The Toxin and Toxin-Target Database (T3DB), also known as the Toxic Exposome Database, is a freely accessible online database of common substances that are toxic to humans, along with their protein, DNA or organ targets. The database currently houses nearly 3,700 toxic compounds or poisons described by nearly 42,000 synonyms.".
- Toxin_and_Toxin-Target_Database label "Toxin and Toxin-Target Database".
- Toxin_and_Toxin-Target_Database sameAs Q7830437.
- Toxin_and_Toxin-Target_Database sameAs m.0h_bg_8.
- Toxin_and_Toxin-Target_Database sameAs Q7830437.
- Toxin_and_Toxin-Target_Database wasDerivedFrom Toxin_and_Toxin-Target_Database?oldid=673382315.
- Toxin_and_Toxin-Target_Database depiction T3db-banner.jpg.
- Toxin_and_Toxin-Target_Database homepage www.t3db.ca.
- Toxin_and_Toxin-Target_Database isPrimaryTopicOf Toxin_and_Toxin-Target_Database.