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- Thromboplastin abstract "Thromboplastin is a plasma protein aiding blood coagulation through catalyzing the conversion of prothrombin to thrombin. It is a complex enzyme that is found in brain, lung, and other tissues and especially in blood platelets and that functions in the conversion of prothrombin to thrombin in the clotting of blood—called also thrombokinaseAlthough sometimes used as a synonym for the protein tissue factor (with its official name \"Coagulation factor III [thromboplastin, tissue factor]\"), this is a misconception. Historically, thromboplastin was a lab reagent, usually derived from placental sources, used to assay prothrombin times (PT time). Thromboplastin, by itself, could activate the extrinsic coagulation pathway. When manipulated in the laboratory, a derivative could be created called partial thromboplastin. Partial thromboplastin was used to measure the intrinsic pathway. This test is called the aPTT, or activated partial thromboplastin time. It was not until much later that the subcomponents of thromboplastin and partial thromboplastin were identified. Thromboplastin is the combination of both phospholipids and tissue factor, both needed in the activation of the extrinsic pathway. However, partial thromboplastin is just phospholipids, and not tissue factor. Currently, recombinant tissue factor is not available and used in some PT assays. Placental derivatives are still available and used in some laboratories. Phospholipid is available as an independent reagent or in combination with tissue factor as thromboplastin. Complete thromboplastin consists of tissue factor, phospholipids (since platelets were removed from blood sample being tested), and CaCl2 to reintroduce calcium ions that were chelated by sodium citrate originally used to prevent coagulation of the sample blood during transportation and/or storage.".
- Thromboplastin wikiPageID "4448027".
- Thromboplastin wikiPageLength "2597".
- Thromboplastin wikiPageOutDegree "13".
- Thromboplastin wikiPageRevisionID "699696043".
- Thromboplastin wikiPageWikiLink Blood_plasma.
- Thromboplastin wikiPageWikiLink Calcium_chloride.
- Thromboplastin wikiPageWikiLink Category:Coagulation_system.
- Thromboplastin wikiPageWikiLink Category:Human_proteins.
- Thromboplastin wikiPageWikiLink Coagulation.
- Thromboplastin wikiPageWikiLink Partial_thromboplastin_time.
- Thromboplastin wikiPageWikiLink Phospholipid.
- Thromboplastin wikiPageWikiLink Placenta.
- Thromboplastin wikiPageWikiLink Protein.
- Thromboplastin wikiPageWikiLink Reagent.
- Thromboplastin wikiPageWikiLink Thrombin.
- Thromboplastin wikiPageWikiLink Tissue_factor.
- Thromboplastin wikiPageWikiLinkText "Thromboplastin".
- Thromboplastin wikiPageWikiLinkText "thromboplastin".
- Thromboplastin wikiPageUsesTemplate Template:MeshName.
- Thromboplastin wikiPageUsesTemplate Template:Refbegin.
- Thromboplastin wikiPageUsesTemplate Template:Refend.
- Thromboplastin wikiPageUsesTemplate Template:Reflist.
- Thromboplastin subject Category:Coagulation_system.
- Thromboplastin subject Category:Human_proteins.
- Thromboplastin hypernym Protein.
- Thromboplastin type Protein.
- Thromboplastin comment "Thromboplastin is a plasma protein aiding blood coagulation through catalyzing the conversion of prothrombin to thrombin.".
- Thromboplastin label "Thromboplastin".
- Thromboplastin sameAs Q6153218.
- Thromboplastin sameAs Tromboplastina.
- Thromboplastin sameAs ترومبوپلاستین.
- Thromboplastin sameAs m.05fc7_m.
- Thromboplastin sameAs Q6153218.
- Thromboplastin wasDerivedFrom Thromboplastin?oldid=699696043.
- Thromboplastin isPrimaryTopicOf Thromboplastin.