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- Tafenoquine abstract "Tafenoquine is an 8-aminoquinoline drug manufactured by GlaxoSmithKline that is being investigated as a potential treatment for malaria, as well as for malaria prevention.The proposed indication for tafenoquine is for treatment of the hypnozoite stages of Plasmodium vivax and Plasmodium ovale that are responsible for relapse of these malaria species even when the blood stages are successfully cleared. This is only now achieved by administration of daily primaquine for 14 days. The main advantage of tafenoquine is that it has a long half-life (2–3 weeks) and therefore a single treatment may be sufficient to clear hypnozoites. The shorter regimen has been described as an advantage.Like primaquine, tafenoquine causes hemolysis in people with G-6-P deficiency. Indeed, the long half-life of tafenoquine suggests that particular care should be taken to ensure that individuals with severe G-6-P deficiency do not receive the drug.The dose of tafenoquine has not been firmly established, but for the treatment of Plasmodium vivax malaria, a dose of 800 mg over three days has been used.".
- Tafenoquine atcPrefix "none".
- Tafenoquine casNumber "106635-80-7".
- Tafenoquine fdaUniiCode "262P8GS9L9".
- Tafenoquine iupacName "N-[2,6-Dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl]pentane-1,4-diamine".
- Tafenoquine pubchem "115358".
- Tafenoquine thumbnail Tafenoquine.svg?width=300.
- Tafenoquine wikiPageID "8955612".
- Tafenoquine wikiPageLength "5529".
- Tafenoquine wikiPageOutDegree "12".
- Tafenoquine wikiPageRevisionID "673331658".
- Tafenoquine wikiPageWikiLink 8-Aminoquinoline.
- Tafenoquine wikiPageWikiLink Category:Antimalarial_agents.
- Tafenoquine wikiPageWikiLink Category:Organofluorides.
- Tafenoquine wikiPageWikiLink Category:Phenol_ethers.
- Tafenoquine wikiPageWikiLink Category:Quinolines.
- Tafenoquine wikiPageWikiLink GlaxoSmithKline.
- Tafenoquine wikiPageWikiLink Glucose-6-phosphate_dehydrogenase_deficiency.
- Tafenoquine wikiPageWikiLink Hemolysis.
- Tafenoquine wikiPageWikiLink Plasmodium.
- Tafenoquine wikiPageWikiLink Plasmodium_ovale.
- Tafenoquine wikiPageWikiLink Plasmodium_vivax.
- Tafenoquine wikiPageWikiLink Primaquine.
- Tafenoquine wikiPageWikiLinkText "Tafenoquine".
- Tafenoquine wikiPageWikiLinkText "tafenoquine".
- Tafenoquine atcPrefix "none".
- Tafenoquine c "24".
- Tafenoquine casNumber "106635".
- Tafenoquine chembl "298470".
- Tafenoquine chemspiderid "103196".
- Tafenoquine f "3".
- Tafenoquine h "28".
- Tafenoquine inchi "1".
- Tafenoquine inchikey "LBHLFPGPEGDCJG-UHFFFAOYAE".
- Tafenoquine iupacName "N-[2,6-Dimethoxy-4-methyl-5-[3-phenoxy]quinolin-8-yl]pentane-1,4-diamine".
- Tafenoquine molecularWeight "463.493".
- Tafenoquine n "3".
- Tafenoquine niaidChemdb "6901".
- Tafenoquine o "3".
- Tafenoquine pubchem "115358".
- Tafenoquine smiles "FCc3ccccc3".
- Tafenoquine stdinchi "1".
- Tafenoquine stdinchikey "LBHLFPGPEGDCJG-UHFFFAOYSA-N".
- Tafenoquine synonyms "Etaquine, WR 238605, SB-252263".
- Tafenoquine unii "262".
- Tafenoquine verifiedfields "changed".
- Tafenoquine verifiedrevid "470476706".
- Tafenoquine watchedfields "changed".
- Tafenoquine wikiPageUsesTemplate Template:Antimalarials.
- Tafenoquine wikiPageUsesTemplate Template:Cascite.
- Tafenoquine wikiPageUsesTemplate Template:Chemspidercite.
- Tafenoquine wikiPageUsesTemplate Template:Drugbankcite.
- Tafenoquine wikiPageUsesTemplate Template:Drugbox.
- Tafenoquine wikiPageUsesTemplate Template:Ebicite.
- Tafenoquine wikiPageUsesTemplate Template:Fdacite.
- Tafenoquine wikiPageUsesTemplate Template:Reflist.
- Tafenoquine wikiPageUsesTemplate Template:Stdinchicite.
- Tafenoquine subject Category:Antimalarial_agents.
- Tafenoquine subject Category:Organofluorides.
- Tafenoquine subject Category:Phenol_ethers.
- Tafenoquine subject Category:Quinolines.
- Tafenoquine hypernym Drug.
- Tafenoquine type Agent.
- Tafenoquine type ChemicalSubstance.
- Tafenoquine type Drug.
- Tafenoquine type Agent.
- Tafenoquine type Chemical.
- Tafenoquine type Drug.
- Tafenoquine type Ether.
- Tafenoquine type Heterocycle.
- Tafenoquine type Organofluoride.
- Tafenoquine type Organohalide.
- Tafenoquine type Organofluoride.
- Tafenoquine type Organohalide.
- Tafenoquine type ChemicalObject.
- Tafenoquine type Thing.
- Tafenoquine type Q8386.
- Tafenoquine comment "Tafenoquine is an 8-aminoquinoline drug manufactured by GlaxoSmithKline that is being investigated as a potential treatment for malaria, as well as for malaria prevention.The proposed indication for tafenoquine is for treatment of the hypnozoite stages of Plasmodium vivax and Plasmodium ovale that are responsible for relapse of these malaria species even when the blood stages are successfully cleared. This is only now achieved by administration of daily primaquine for 14 days.".
- Tafenoquine label "Tafenoquine".
- Tafenoquine sameAs Q2387553.
- Tafenoquine sameAs Tafenoquin.
- Tafenoquine sameAs Tafenoquine.
- Tafenoquine sameAs m.027r3kh.
- Tafenoquine sameAs Tafenokvin.
- Tafenoquine sameAs Tafenokvin.
- Tafenoquine sameAs Q2387553.
- Tafenoquine wasDerivedFrom Tafenoquine?oldid=673331658.
- Tafenoquine depiction Tafenoquine.svg.
- Tafenoquine isPrimaryTopicOf Tafenoquine.
