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- TUBB3 abstract "Tubulin beta-3 chain is a protein that in humans is encoded by the TUBB3 gene.Class III β-tubulin is one of the seven β-tubulin isotypes identified in the human genome. In humans, this protein is encoded by the TUBB3 gene. Class III β-tubulin is constitutively expressed in neural tissues. and in testis cells and conditionally expressed in a number of other tissues after exposure to a toxic microenvironment featured by hypoxia and poor nutrient supply. Posttranslational changes including phosphorylation and glycosylation are required for functional activity.Class III β-tubulin’s role in neural development has warranted its use as an early biomarker of neural cell differentiation from multi potent progenitors. TUBB3 inactivation impairs neural progenitor proliferation. Rescue experiments demonstrate the non-interchangeability of TUBB3 with other classes of β-tubulins which cannot restore the phenotype resulting from TUBB3 inactivation. Congenital neurologic syndromes associated with TUBB3 missense mutations demonstrate the critical importance of class III β-tubulin for normal neural development.".
- TUBB3 entrezgene "10381".
- TUBB3 wikiPageID "14762781".
- TUBB3 wikiPageLength "21986".
- TUBB3 wikiPageOutDegree "12".
- TUBB3 wikiPageRevisionID "704780199".
- TUBB3 wikiPageWikiLink Cytoskeleton.
- TUBB3 wikiPageWikiLink FMO4.
- TUBB3 wikiPageWikiLink GBP1.
- TUBB3 wikiPageWikiLink GSTM4.
- TUBB3 wikiPageWikiLink Gene.
- TUBB3 wikiPageWikiLink Hypoxia_(medical).
- TUBB3 wikiPageWikiLink Interactome.
- TUBB3 wikiPageWikiLink NEK6.
- TUBB3 wikiPageWikiLink PIM1.
- TUBB3 wikiPageWikiLink Protein.
- TUBB3 wikiPageWikiLink Testicle.
- TUBB3 wikiPageWikiLink Tubulin.
- TUBB3 wikiPageWikiLinkText "TUBB3".
- TUBB3 wikiPageUsesTemplate Template:Merge_from.
- TUBB3 wikiPageUsesTemplate Template:PBB.
- TUBB3 wikiPageUsesTemplate Template:PDB_Gallery.
- TUBB3 wikiPageUsesTemplate Template:Reflist.
- TUBB3 hypernym Protein.
- TUBB3 type Biomolecule.
- TUBB3 type Protein.
- TUBB3 type Thing.
- TUBB3 type Q206229.
- TUBB3 type Q8054.
- TUBB3 comment "Tubulin beta-3 chain is a protein that in humans is encoded by the TUBB3 gene.Class III β-tubulin is one of the seven β-tubulin isotypes identified in the human genome. In humans, this protein is encoded by the TUBB3 gene. Class III β-tubulin is constitutively expressed in neural tissues. and in testis cells and conditionally expressed in a number of other tissues after exposure to a toxic microenvironment featured by hypoxia and poor nutrient supply.".
- TUBB3 label "TUBB3".
- TUBB3 sameAs Q18035338.
- TUBB3 sameAs m.03gx43j.
- TUBB3 sameAs Q18035338.
- TUBB3 wasDerivedFrom TUBB3?oldid=704780199.
- TUBB3 isPrimaryTopicOf TUBB3.