Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/TP53-inducible_glycolysis_and_apoptosis_regulator> ?p ?o }
- TP53-inducible_glycolysis_and_apoptosis_regulator abstract "The TP53-inducible glycolysis and apoptosis regulator (TIGAR) also known as fructose-2,6-bisphosphatase TIGAR is an enzyme that in humans is encoded by the C12orf5 gene.TIGAR is a recently discovered enzyme that primarily functions as a regulator of glucose breakdown in human cells. In addition to its role in controlling glucose degradation, TIGAR activity can allow a cell to carry out DNA repair, and the degradation of its own organelles. Finally, TIGAR can protect a cell from death. Since its discovery in 2005 by Kuang-Yu Jen and Vivian G. Cheung, TIGAR has become of particular interest to the scientific community thanks to its active role in many cancers. Normally, TIGAR manufacture by the body is activated by the p53 tumour suppressor protein after a cell has experienced a low level of DNA damage or stress. In some cancers, TIGAR has fallen under the control of other proteins. The hope is that future research into TIGAR will provide insight into new ways to treat cancer.This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region.".
- TP53-inducible_glycolysis_and_apoptosis_regulator entrezgene "57103".
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageID "38879444".
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageLength "26726".
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageOutDegree "119".
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageRevisionID "699479113".
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Active_site.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Adenosine_diphosphate.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Adenosine_triphosphate.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Allosteric_regulation.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Alpha_helix.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Amino_acid.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Anabolism.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Anaerobic_respiration.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Apoptosis.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Base_pair.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Bcl-2-associated_X_protein.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Beta_sheet.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Biomolecular_structure.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Bisphosphate.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink C-Met.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink C-terminus.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Cancer.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Carbohydrate_metabolism.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Carcinogenesis.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Caspase.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Catalysis.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Catalytic_triad.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Category:Apoptosis.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Category:Glycolysis.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Category:Human_genes.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Category:Human_proteins.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Cell_(biology).
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Cell_culture.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Cell_cycle.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Cell_cycle_checkpoint.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Cell_division.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Cellular_respiration.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Chromosome.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Cyclin.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Cyclin-dependent_kinase.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Cyclin-dependent_kinase_2.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Cyclin-dependent_kinase_4.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Cyclin_D.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Cyclin_E.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Cytochrome_c.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Cytoplasm.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink DNA.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink DNA_repair.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink E2F.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Electron.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Electron_transport_chain.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Electrostatics.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Enzyme.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Exon.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Fructose_2,6-bisphosphate.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink G1_phase.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Gene.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Glioma.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Gluconeogenesis.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Glucose.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Glutamic_acid.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Glutathione.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Glycolysis.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Growth_factor.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink HAMP_domain.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink HIF1A.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink HK2.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Hydrogen_peroxide.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Hypoxia_(medical).
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Interleukin.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Intracellular.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Intron.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Ion.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Ionizing_radiation.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Isomerization.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Macromolecule.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Mammal.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Membrane.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Membrane_potential.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Messenger_RNA.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Mitochondrion.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Multiple_myeloma.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Nicotinamide_adenine_dinucleotide.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Nicotinamide_adenine_dinucleotide_phosphate.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Nucleic_acid.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Oncogene.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Organelle.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink P53.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Pentose_phosphate_pathway.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Pharynx.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Phosphatase.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Phosphate.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Phosphofructokinase_1.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Phosphofructokinase_2.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Phosphoglycerate_mutase.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Protein.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Reactive_oxygen_species.
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Receptor_(biochemistry).
- TP53-inducible_glycolysis_and_apoptosis_regulator wikiPageWikiLink Redox.