Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Sulfatide> ?p ?o }
- Sulfatide abstract "Sulfatide, also known as 3-O-sulfogalactosylceramide, SM4, or sulfated galactocerebroside, is a class of sulfolipids, specifically a class of sulfoglycolipids, which are glycolipids that contain a sulfate group. Sulfatide is synthesized primarily starting in the endoplasmic reticulum and ending in the Golgi apparatus where ceramide is converted to galactocerebroside and later sulfated to make sulfatide. Of all of the galactolipids that are found in the myelin sheath, one fifth of them are sulfatide. Sulfatide is primarily found on the extracellular leaflet of the myelin plasma membrane produced by the oligodendrocytes in the central nervous system and in the Schwann cells in the peripheral nervous system. However, sulfatide is also present on the extracellular leaflet of the plasma membrane of many cells in eukaryotic organisms.Since sulfatide is a multifunctional molecule, it can be used in multiple biological areas. Aside from being a membrane component, sulfatide functions in protein trafficking, cell aggregation and adhesion, neural plasticity, memory, and glial-axon interactions. Sulfatide also plays a role in several physiological processes and systems including, the nervous system, the immune system, insulin secretion, blood clotting, viral infection, and bacterial infection. As a result, sulfatide is associated with, able to bind to, and/or is present in kidney tissues, cancer cells/ tissues, the surface of red blood cells and platelets, CD1 a-d cells in the immune system, many bacteria cells, several viruses, myelin, neurons, and astrocytes.An abnormal metabolism or change in the expression of sulfatide has also been associated with various pathologies including neuropathologies, such as metachromatic leukodystrophy, Alzheimer's disease, and Parkinson's Disease. Sulfatide is also associated with diabetes mellitus, cancer metastasis, and viruses including HIV-1, influenza A virus, hepatitis C and vaccinia virus. Additionally, overexpression of sulfatide has been linked to epilepsy and audiogenic seizures as well as other pathological states in the nervous system.Past and ongoing research continues to elucidate the many biological functions of sulfatide and their many implications as well as the pathology that has been associated with sulfatide. Most research utilizes mice models, but heterologous expression systems are utilized as well, including but not limited to, Madin-Darby canine kidney cells and COS-7 Cells.".
- Sulfatide thumbnail Sulfatide.png?width=300.
- Sulfatide wikiPageID "6021647".
- Sulfatide wikiPageLength "46949".
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- Sulfatide wikiPageRevisionID "698320846".
- Sulfatide wikiPageWikiLink 3-Phosphoadenosine-5-phosphosulfate.
- Sulfatide wikiPageWikiLink Actinobacillus_pleuropneumoniae.
- Sulfatide wikiPageWikiLink Adeno-associated_virus.
- Sulfatide wikiPageWikiLink Adenocarcinoma.
- Sulfatide wikiPageWikiLink Adenocarcinoma_of_the_lung.
- Sulfatide wikiPageWikiLink Adenosine_triphosphate.
- Sulfatide wikiPageWikiLink Alzheimers_disease.
- Sulfatide wikiPageWikiLink Amide.
- Sulfatide wikiPageWikiLink Amyloid_beta.
- Sulfatide wikiPageWikiLink Angiogenesis.
- Sulfatide wikiPageWikiLink Annexin_A5.
- Sulfatide wikiPageWikiLink Antagonist.
- Sulfatide wikiPageWikiLink Anti-inflammatory.
- Sulfatide wikiPageWikiLink Antibody.
- Sulfatide wikiPageWikiLink Antigen.
- Sulfatide wikiPageWikiLink Apolipoprotein_E.
- Sulfatide wikiPageWikiLink Apoptosis.
- Sulfatide wikiPageWikiLink Artifact_(error).
- Sulfatide wikiPageWikiLink Arylsulfatase_A.
- Sulfatide wikiPageWikiLink Astrocyte.
- Sulfatide wikiPageWikiLink Ataxia.
- Sulfatide wikiPageWikiLink Audiogenic.
- Sulfatide wikiPageWikiLink Autoimmune_disease.
- Sulfatide wikiPageWikiLink Autoimmunity.
- Sulfatide wikiPageWikiLink Axon.
- Sulfatide wikiPageWikiLink B_cell.
- Sulfatide wikiPageWikiLink Bacteria.
- Sulfatide wikiPageWikiLink Benignity.
- Sulfatide wikiPageWikiLink Beta_cell.
- Sulfatide wikiPageWikiLink Biomarker.
- Sulfatide wikiPageWikiLink Biosynthesis.
- Sulfatide wikiPageWikiLink Bordetella_pertussis.
- Sulfatide wikiPageWikiLink Brain.
- Sulfatide wikiPageWikiLink CD1.
- Sulfatide wikiPageWikiLink CD1D.
- Sulfatide wikiPageWikiLink CD4.
- Sulfatide wikiPageWikiLink CNTN1.
- Sulfatide wikiPageWikiLink CXCR4.
- Sulfatide wikiPageWikiLink Calcium.
- Sulfatide wikiPageWikiLink Campylobacter_jejuni.
- Sulfatide wikiPageWikiLink Cancer.
- Sulfatide wikiPageWikiLink Carbonyl_sulfide.
- Sulfatide wikiPageWikiLink Carcinoma.
- Sulfatide wikiPageWikiLink Cardiovascular_disease.
- Sulfatide wikiPageWikiLink Caspr.
- Sulfatide wikiPageWikiLink Category:Glycolipids.
- Sulfatide wikiPageWikiLink Category:Organosulfates.
- Sulfatide wikiPageWikiLink Cell_adhesion.
- Sulfatide wikiPageWikiLink Cell_membrane.
- Sulfatide wikiPageWikiLink Cellular_differentiation.
- Sulfatide wikiPageWikiLink Central_nervous_system.
- Sulfatide wikiPageWikiLink Ceramide.
- Sulfatide wikiPageWikiLink Cerebellum.
- Sulfatide wikiPageWikiLink Cerebrospinal_fluid.
- Sulfatide wikiPageWikiLink Cerebrum.
- Sulfatide wikiPageWikiLink Chaperone_(protein).
- Sulfatide wikiPageWikiLink Chemical_structure.
- Sulfatide wikiPageWikiLink Chemokine.
- Sulfatide wikiPageWikiLink Cholesterol.
- Sulfatide wikiPageWikiLink Coagulation.
- Sulfatide wikiPageWikiLink Colorectal_cancer.
- Sulfatide wikiPageWikiLink Cryoglobulinemia.
- Sulfatide wikiPageWikiLink Cytokine.
- Sulfatide wikiPageWikiLink Dementia.
- Sulfatide wikiPageWikiLink Demyelinating_disease.
- Sulfatide wikiPageWikiLink Dendritic_cell.
- Sulfatide wikiPageWikiLink Diabetes_mellitus.
- Sulfatide wikiPageWikiLink Diabetes_mellitus_type_1.
- Sulfatide wikiPageWikiLink Diabetes_mellitus_type_2.
- Sulfatide wikiPageWikiLink Domestic_pig.
- Sulfatide wikiPageWikiLink Dominance_(genetics).
- Sulfatide wikiPageWikiLink Downregulation_and_upregulation.
- Sulfatide wikiPageWikiLink Embryogenesis.
- Sulfatide wikiPageWikiLink Endocytosis.
- Sulfatide wikiPageWikiLink Endoplasmic_reticulum.
- Sulfatide wikiPageWikiLink Enterotoxin.
- Sulfatide wikiPageWikiLink Envelope_glycoprotein_GP120.
- Sulfatide wikiPageWikiLink Enzyme.
- Sulfatide wikiPageWikiLink Enzyme_replacement_therapy.
- Sulfatide wikiPageWikiLink Epidermal_growth_factor.
- Sulfatide wikiPageWikiLink Epilepsy.
- Sulfatide wikiPageWikiLink Epileptic_seizure.
- Sulfatide wikiPageWikiLink Epithelium.
- Sulfatide wikiPageWikiLink Escherichia_coli.
- Sulfatide wikiPageWikiLink Eukaryote.
- Sulfatide wikiPageWikiLink Exocytosis.
- Sulfatide wikiPageWikiLink Extracellular_matrix.
- Sulfatide wikiPageWikiLink Factor_XII.
- Sulfatide wikiPageWikiLink Fatty_acid.
- Sulfatide wikiPageWikiLink Fibrin.
- Sulfatide wikiPageWikiLink Fibrinogen.
- Sulfatide wikiPageWikiLink Frontal_lobe.
- Sulfatide wikiPageWikiLink Funen.
- Sulfatide wikiPageWikiLink Galactocerebroside.