Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Strontium_ranelate> ?p ?o }
- Strontium_ranelate abstract "Strontium ranelate, a strontium(II) salt of ranelic acid, is a medication for osteoporosis marketed as Protelos or Protos by Servier. Studies indicate it can also slow the course of osteoarthritis of the knee. The drug is unusual in that it both increases deposition of new bone by osteoblasts and reduces the resorption of bone by osteoclasts. It is therefore promoted as a \"dual action bone agent\" (DABA).On 13 May 2013, Servier released a Direct Healthcare Professional Communication which stated that new restrictions for the use of strontium ranelate are now in place, as randomised trials have shown an increased risk of myocardial infarction. Servier states that the use is now restricted to treatment of severe osteoporosis in postmenopausal women at high risk for fracture. The European Pharmacovigilance Risk Assessment Committee (PRAC) recommends restriction in the use of strontium ranelate, based on a routine benefit-risk assessment of the medicine, which included data showing an increased risk of heart problems, including heart attacks. On 21 February 2014 the European Medicine Agency recommended that strontium ranelate remain available with restrictions relative to patients with existing heart disease.".
- Strontium_ranelate atcPrefix "M05".
- Strontium_ranelate atcSuffix "BX03".
- Strontium_ranelate bioavailability "25.0".
- Strontium_ranelate casNumber "135459-90-4".
- Strontium_ranelate fdaUniiCode "04NQ160FRU".
- Strontium_ranelate iupacName "3-(2-oxido-2-oxoethyl)thiophene-2-carboxylate".
- Strontium_ranelate iupacName "distrontium 5-[bis(2-oxido-2-oxoethyl)amino]-4-cyano-".
- Strontium_ranelate pubchem "6918182".
- Strontium_ranelate thumbnail Strontium_ranelate.svg?width=300.
- Strontium_ranelate wikiPageExternalLink printerfriendlynews.php?newsid=132149.
- Strontium_ranelate wikiPageExternalLink news_detail_002005.jsp&mid=WC0b01ac058004d5c1.
- Strontium_ranelate wikiPageExternalLink www.protelos.com.
- Strontium_ranelate wikiPageID "10053205".
- Strontium_ranelate wikiPageLength "12090".
- Strontium_ranelate wikiPageOutDegree "36".
- Strontium_ranelate wikiPageRevisionID "706838586".
- Strontium_ranelate wikiPageWikiLink Body_mass_index.
- Strontium_ranelate wikiPageWikiLink Bone_density.
- Strontium_ranelate wikiPageWikiLink Calcium.
- Strontium_ranelate wikiPageWikiLink Category:Osteoporosis_drugs.
- Strontium_ranelate wikiPageWikiLink Category:Strontium_compounds.
- Strontium_ranelate wikiPageWikiLink Chelation.
- Strontium_ranelate wikiPageWikiLink Cytochrome_P450.
- Strontium_ranelate wikiPageWikiLink DRESS_syndrome.
- Strontium_ranelate wikiPageWikiLink Dermatitis.
- Strontium_ranelate wikiPageWikiLink Diarrhea.
- Strontium_ranelate wikiPageWikiLink Food_and_Drug_Administration.
- Strontium_ranelate wikiPageWikiLink Gastrointestinal_tract.
- Strontium_ranelate wikiPageWikiLink Headache.
- Strontium_ranelate wikiPageWikiLink Hip_fracture.
- Strontium_ranelate wikiPageWikiLink Kidney.
- Strontium_ranelate wikiPageWikiLink Laboratoires_Servier.
- Strontium_ranelate wikiPageWikiLink Menopause.
- Strontium_ranelate wikiPageWikiLink Myocardial_infarction.
- Strontium_ranelate wikiPageWikiLink National_Health_Service.
- Strontium_ranelate wikiPageWikiLink Nausea.
- Strontium_ranelate wikiPageWikiLink Osteoarthritis.
- Strontium_ranelate wikiPageWikiLink Osteoblast.
- Strontium_ranelate wikiPageWikiLink Osteoclast.
- Strontium_ranelate wikiPageWikiLink Osteoporosis.
- Strontium_ranelate wikiPageWikiLink Osteoprotegerin.
- Strontium_ranelate wikiPageWikiLink Quinolone.
- Strontium_ranelate wikiPageWikiLink RANKL.
- Strontium_ranelate wikiPageWikiLink Ranelic_acid.
- Strontium_ranelate wikiPageWikiLink Renal_function.
- Strontium_ranelate wikiPageWikiLink Salt_(chemistry).
- Strontium_ranelate wikiPageWikiLink Strontium.
- Strontium_ranelate wikiPageWikiLink Tetracycline.
- Strontium_ranelate wikiPageWikiLink Venous_thrombosis.
- Strontium_ranelate wikiPageWikiLinkText "Strontium ranelate".
- Strontium_ranelate wikiPageWikiLinkText "strontium ranelate".
- Strontium_ranelate atcPrefix "M05".
- Strontium_ranelate atcSuffix "BX03".
- Strontium_ranelate bioavailability "25.0".
- Strontium_ranelate c "12".
- Strontium_ranelate casNumber "135459".
- Strontium_ranelate chemspiderid "5293393".
- Strontium_ranelate eliminationHalfLife "216000.0".
- Strontium_ranelate excretion "Renal and gastrointestinal. Plasma clearance is about 12 ml/min and renal clearance about 7 ml/min".
- Strontium_ranelate h "6".
- Strontium_ranelate image "Strontium ranelate 3D.png".
- Strontium_ranelate inchi "1".
- Strontium_ranelate inchikey "XXUZFRDUEGQHOV-XBHQNQODAM".
- Strontium_ranelate iupacName "3".
- Strontium_ranelate iupacName "distrontium 5-[bisamino]-4-cyano-".
- Strontium_ranelate kegg "D08468".
- Strontium_ranelate legalUk "POM".
- Strontium_ranelate metabolism "As a divalent cation, strontium is not metabolised. Does not inhibit cytochrome P450 enzymes".
- Strontium_ranelate molecularWeight "513.491".
- Strontium_ranelate n "2".
- Strontium_ranelate o "8".
- Strontium_ranelate pregnancyCategory "Only intended for use in postmenopausal women, no data on exposed pregnancies. If strontium ranelate is used inadvertently during pregnancy, treatment must be stopped.".
- Strontium_ranelate proteinBound "25".
- Strontium_ranelate pubchem "6918182".
- Strontium_ranelate routesOfAdministration "Oral".
- Strontium_ranelate s "1".
- Strontium_ranelate smiles "[Sr+2].[Sr+2].O=CCNCC=O".
- Strontium_ranelate sr "2".
- Strontium_ranelate stdinchi "1".
- Strontium_ranelate stdinchikey "XXUZFRDUEGQHOV-UHFFFAOYSA-J".
- Strontium_ranelate unii "4".
- Strontium_ranelate verifiedfields "changed".
- Strontium_ranelate verifiedrevid "470471557".
- Strontium_ranelate wikiPageUsesTemplate Template:Cascite.
- Strontium_ranelate wikiPageUsesTemplate Template:Chemspidercite.
- Strontium_ranelate wikiPageUsesTemplate Template:Cite_news.
- Strontium_ranelate wikiPageUsesTemplate Template:Drugbankcite.
- Strontium_ranelate wikiPageUsesTemplate Template:Drugbox.
- Strontium_ranelate wikiPageUsesTemplate Template:Drugs_for_treatment_of_bone_diseases.
- Strontium_ranelate wikiPageUsesTemplate Template:Fdacite.
- Strontium_ranelate wikiPageUsesTemplate Template:Reflist.
- Strontium_ranelate wikiPageUsesTemplate Template:Stdinchicite.
- Strontium_ranelate subject Category:Osteoporosis_drugs.
- Strontium_ranelate subject Category:Strontium_compounds.
- Strontium_ranelate hypernym Medication.
- Strontium_ranelate type ChemicalSubstance.
- Strontium_ranelate type Drug.
- Strontium_ranelate type Drug.
- Strontium_ranelate type Redirect.