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- Silent_mutation abstract "Silent mutations are mutations in DNA that do not significantly alter the phenotype of the organism in which they occur. Silent mutations can occur in non-coding regions (outside of genes or within introns), or they may occur within exons. When they occur within exons they either do not result in a change to the amino acid sequence of a protein (a \"synonymous substitution\"), or result in the insertion of an alternative amino acid with similar properties to that of the original amino acid; in either case there is no significant change in phenotype. The phrase silent mutation is often used interchangeably with the phrase synonymous mutation; however, synonymous mutations only occur within exons, and are not always silent mutations. Synonymous mutations can affect transcription, splicing, mRNA transport, and translation, any of which could alter phenotype, rendering the synonymous mutation non-silent. The substrate specificity of the tRNA to the rare codon can affect the timing of translation, and in turn the co-translational folding of the protein. This is reflected in the codon usage bias that is observed in many species. Mutations that cause the altered codon to produce an amino acid with similar functionality (e.g. a mutation producing leucine instead of isoleucine) are often classified as silent; if the properties of the amino acid are conserved, this mutation does not usually significantly affect protein function.".
- Silent_mutation thumbnail Different_Types_of_Mutations.png?width=300.
- Silent_mutation wikiPageExternalLink template.php.
- Silent_mutation wikiPageExternalLink the-price-of-silent-mutations.
- Silent_mutation wikiPageID "1260905".
- Silent_mutation wikiPageLength "15457".
- Silent_mutation wikiPageOutDegree "66".
- Silent_mutation wikiPageRevisionID "707132204".
- Silent_mutation wikiPageWikiLink Amino_acid.
- Silent_mutation wikiPageWikiLink Attenuated_vaccine.
- Silent_mutation wikiPageWikiLink Biomolecular_structure.
- Silent_mutation wikiPageWikiLink Category:Molecular_evolution.
- Silent_mutation wikiPageWikiLink Category:Mutation.
- Silent_mutation wikiPageWikiLink Cloning.
- Silent_mutation wikiPageWikiLink Codon_usage_bias.
- Silent_mutation wikiPageWikiLink Cytoplasm.
- Silent_mutation wikiPageWikiLink DNA.
- Silent_mutation wikiPageWikiLink Degeneracy_(biology).
- Silent_mutation wikiPageWikiLink Dopamine_receptor_D2.
- Silent_mutation wikiPageWikiLink Exon.
- Silent_mutation wikiPageWikiLink File:Different_Types_of_Mutations.png.
- Silent_mutation wikiPageWikiLink Frameshift_mutation.
- Silent_mutation wikiPageWikiLink Gene.
- Silent_mutation wikiPageWikiLink Genealogical_DNA_test.
- Silent_mutation wikiPageWikiLink Genetic_code.
- Silent_mutation wikiPageWikiLink Intron.
- Silent_mutation wikiPageWikiLink Isoleucine.
- Silent_mutation wikiPageWikiLink Leucine.
- Silent_mutation wikiPageWikiLink Lysine.
- Silent_mutation wikiPageWikiLink Messenger_RNA.
- Silent_mutation wikiPageWikiLink Missense_mutation.
- Silent_mutation wikiPageWikiLink Mutation.
- Silent_mutation wikiPageWikiLink Natural_selection.
- Silent_mutation wikiPageWikiLink Neutral_theory_of_molecular_evolution.
- Silent_mutation wikiPageWikiLink Noncoding_DNA.
- Silent_mutation wikiPageWikiLink Nonsense_mutation.
- Silent_mutation wikiPageWikiLink P-glycoprotein.
- Silent_mutation wikiPageWikiLink Peptide.
- Silent_mutation wikiPageWikiLink Phenotype.
- Silent_mutation wikiPageWikiLink Point_mutation.
- Silent_mutation wikiPageWikiLink Poliomyelitis.
- Silent_mutation wikiPageWikiLink Protein.
- Silent_mutation wikiPageWikiLink RNA_splicing.
- Silent_mutation wikiPageWikiLink Reading_frame.
- Silent_mutation wikiPageWikiLink Restriction_enzyme.
- Silent_mutation wikiPageWikiLink Ribosome.
- Silent_mutation wikiPageWikiLink Serine.
- Silent_mutation wikiPageWikiLink Silent_mutation.
- Silent_mutation wikiPageWikiLink Start_codon.
- Silent_mutation wikiPageWikiLink Steffen_Mueller.
- Silent_mutation wikiPageWikiLink Stop_codon.
- Silent_mutation wikiPageWikiLink Synonym.
- Silent_mutation wikiPageWikiLink Synonymous_substitution.
- Silent_mutation wikiPageWikiLink Transcription_(genetics).
- Silent_mutation wikiPageWikiLink Transfer_RNA.
- Silent_mutation wikiPageWikiLink Translation_(biology).
- Silent_mutation wikiPageWikiLinkText "Silent mutation".
- Silent_mutation wikiPageWikiLinkText "non-silent".
- Silent_mutation wikiPageWikiLinkText "silent mutation".
- Silent_mutation wikiPageWikiLinkText "silent polymorphisms".
- Silent_mutation wikiPageWikiLinkText "silent".
- Silent_mutation wikiPageUsesTemplate Template:Cite_journal.
- Silent_mutation wikiPageUsesTemplate Template:Cite_web.
- Silent_mutation wikiPageUsesTemplate Template:Commons_category.
- Silent_mutation wikiPageUsesTemplate Template:MolecularEvolution.
- Silent_mutation wikiPageUsesTemplate Template:Mutation.
- Silent_mutation wikiPageUsesTemplate Template:Reflist.
- Silent_mutation subject Category:Molecular_evolution.
- Silent_mutation subject Category:Mutation.
- Silent_mutation hypernym Mutations.
- Silent_mutation type Protein.
- Silent_mutation type Process.
- Silent_mutation comment "Silent mutations are mutations in DNA that do not significantly alter the phenotype of the organism in which they occur. Silent mutations can occur in non-coding regions (outside of genes or within introns), or they may occur within exons.".
- Silent_mutation label "Silent mutation".
- Silent_mutation sameAs Q2717121.
- Silent_mutation sameAs Mutació_silenciosa.
- Silent_mutation sameAs Category:Silent_mutation.
- Silent_mutation sameAs Tichá_mutace.
- Silent_mutation sameAs Hiljainen_mutaatio.
- Silent_mutation sameAs Mutation_silencieuse.
- Silent_mutation sameAs מוטציה_שקטה.
- Silent_mutation sameAs 非表現突然変異.
- Silent_mutation sameAs Mutacja_cicha.
- Silent_mutation sameAs m.04n18s.
- Silent_mutation sameAs Tyst_mutation.
- Silent_mutation sameAs Q2717121.
- Silent_mutation wasDerivedFrom Silent_mutation?oldid=707132204.
- Silent_mutation depiction Different_Types_of_Mutations.png.
- Silent_mutation isPrimaryTopicOf Silent_mutation.