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- Shinya_Inoué abstract "Shinya Inoué (井上 信也, Inoue Shin'ya, born January 5, 1921) is a Japanese-born American biophysicist and cell biologist, a member of the National Academy of Sciences. His research field is the visualization of dynamic processes within living cells using light microscopy. Currently he is a researcher at the Marine Biological Laboratory.Inoue can be considered the father of the field of cytoskeleton dynamics. In the 1940s and 50s he built the first microscope capable of imaging dynamic processes in live cells, using polarized light, and proved for the first time that the mitotic spindle is composed of aligned protein fibers. We now know these fibers are microtubules. By perturbing cells with agents that cause microtubules to depolymerize (e.g. colchicine or high pressure) or polymerize excessively (e.g. D2O), Inoue demonstrated that spindle fibers are in a state of rapid dynamic equilibrium with a pool of soluble subunits in the cytoplasm. He went on to show that artificial polymerization and depolymerization of spindle fibers can generate forces within the cell, and proposed that chromosomes are normally moved by such forces during mitosis. These ideas were summarized in a seminal review in 1967. He also was the first to develop video microscopy, and wrote a major textbook on the subject. Consistent with Inoue's pioneering ideas, it is now widely believed that chromosome movement during mitosis is powered by microtubule depolymerization. We also know that force generation by polymerization and depolymerization of cytoskeletal protein fibers is perhaps the most ancient of motile mechanisms within cells, whose use extends back to bacteria.".
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- Shinya_Inoué wikiPageExternalLink shinya-inoue-the-dynamic-mitotic-spindle.html.
- Shinya_Inoué wikiPageExternalLink 2010_pr_05_26.html.
- Shinya_Inoué wikiPageExternalLink lab_inoue.html.
- Shinya_Inoué wikiPageExternalLink 04.
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- Shinya_Inoué wikiPageRevisionID "706232060".
- Shinya_Inoué wikiPageWikiLink Biophysics.
- Shinya_Inoué wikiPageWikiLink Category:1921_births.
- Shinya_Inoué wikiPageWikiLink Category:American_academics_of_Japanese_descent.
- Shinya_Inoué wikiPageWikiLink Category:American_biophysicists.
- Shinya_Inoué wikiPageWikiLink Category:American_people_of_Japanese_descent.
- Shinya_Inoué wikiPageWikiLink Category:American_scientists_of_Japanese_descent.
- Shinya_Inoué wikiPageWikiLink Category:Cell_biologists.
- Shinya_Inoué wikiPageWikiLink Category:Japanese_biologists.
- Shinya_Inoué wikiPageWikiLink Category:Japanese_biophysicists.
- Shinya_Inoué wikiPageWikiLink Category:Japanese_emigrants_to_the_United_States.
- Shinya_Inoué wikiPageWikiLink Category:Japanese_scientists.
- Shinya_Inoué wikiPageWikiLink Category:Living_people.
- Shinya_Inoué wikiPageWikiLink Category:Members_of_the_United_States_National_Academy_of_Sciences.
- Shinya_Inoué wikiPageWikiLink Category:Princeton_University_alumni.
- Shinya_Inoué wikiPageWikiLink Category:University_of_Tokyo_alumni.
- Shinya_Inoué wikiPageWikiLink Cell_biology.
- Shinya_Inoué wikiPageWikiLink Chromosome.
- Shinya_Inoué wikiPageWikiLink Colchicine.
- Shinya_Inoué wikiPageWikiLink Cytoplasm.
- Shinya_Inoué wikiPageWikiLink Cytoskeleton.
- Shinya_Inoué wikiPageWikiLink E.B._Wilson_Medal.
- Shinya_Inoué wikiPageWikiLink Guggenheim_Fellowship.
- Shinya_Inoué wikiPageWikiLink International_Prize_for_Biology.
- Shinya_Inoué wikiPageWikiLink Japan_Society_for_the_Promotion_of_Science.
- Shinya_Inoué wikiPageWikiLink Marine_Biological_Laboratory.
- Shinya_Inoué wikiPageWikiLink Microscopy.
- Shinya_Inoué wikiPageWikiLink Microtubule.
- Shinya_Inoué wikiPageWikiLink Mitosis.
- Shinya_Inoué wikiPageWikiLink National_Academy_of_Sciences.
- Shinya_Inoué wikiPageWikiLink Order_of_the_Sacred_Treasure.
- Shinya_Inoué wikiPageWikiLink Polarization_(waves).
- Shinya_Inoué wikiPageWikiLink Princeton_University.
- Shinya_Inoué wikiPageWikiLink Spindle_apparatus.
- Shinya_Inoué wikiPageWikiLink University_of_Tokyo.
- Shinya_Inoué wikiPageWikiLinkText "Shinya Inoué".
- Shinya_Inoué wikiPageUsesTemplate Template:Authority_control.
- Shinya_Inoué wikiPageUsesTemplate Template:More_footnotes.
- Shinya_Inoué wikiPageUsesTemplate Template:Nihongo.
- Shinya_Inoué wikiPageUsesTemplate Template:Reflist.
- Shinya_Inoué subject Category:1921_births.
- Shinya_Inoué subject Category:American_academics_of_Japanese_descent.
- Shinya_Inoué subject Category:American_biophysicists.
- Shinya_Inoué subject Category:American_people_of_Japanese_descent.
- Shinya_Inoué subject Category:American_scientists_of_Japanese_descent.
- Shinya_Inoué subject Category:Cell_biologists.
- Shinya_Inoué subject Category:Japanese_biologists.
- Shinya_Inoué subject Category:Japanese_biophysicists.
- Shinya_Inoué subject Category:Japanese_emigrants_to_the_United_States.
- Shinya_Inoué subject Category:Japanese_scientists.
- Shinya_Inoué subject Category:Living_people.
- Shinya_Inoué subject Category:Members_of_the_United_States_National_Academy_of_Sciences.
- Shinya_Inoué subject Category:Princeton_University_alumni.
- Shinya_Inoué subject Category:University_of_Tokyo_alumni.
- Shinya_Inoué hypernym Biophysicist.
- Shinya_Inoué type List.
- Shinya_Inoué type Scientist.
- Shinya_Inoué type Diacritic.
- Shinya_Inoué type List.
- Shinya_Inoué type Member.
- Shinya_Inoué type Redirect.
- Shinya_Inoué type Scientist.
- Shinya_Inoué type Thing.
- Shinya_Inoué comment "Shinya Inoué (井上 信也, Inoue Shin'ya, born January 5, 1921) is a Japanese-born American biophysicist and cell biologist, a member of the National Academy of Sciences. His research field is the visualization of dynamic processes within living cells using light microscopy. Currently he is a researcher at the Marine Biological Laboratory.Inoue can be considered the father of the field of cytoskeleton dynamics.".
- Shinya_Inoué label "Shinya Inoué".
- Shinya_Inoué sameAs Q1516739.
- Shinya_Inoué sameAs Shinya_Inoué.
- Shinya_Inoué sameAs 井上信也.
- Shinya_Inoué sameAs m.05c1tdg.
- Shinya_Inoué sameAs Q1516739.
- Shinya_Inoué wasDerivedFrom Shinya_Inoué?oldid=706232060.
- Shinya_Inoué isPrimaryTopicOf Shinya_Inoué.