Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Setipiprant> ?p ?o }
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- Setipiprant abstract "Setipiprant (INN) (developmental code names ACT-129,968, KYTH-105) is a drug originally developed by Actelion which acts as a selective, orally available antagonist of the prostaglandin D2 receptor 2 (DP2). It was initially researched as a treatment for allergies and inflammatory disorders, particularly asthma, but despite being well tolerated in clinical trials and showing reasonable efficacy against allergen-induced airway responses in asthmatic patients, it failed to show sufficient advantages over existing drugs and was discontinued from further development in this application.However, following the discovery in 2012 that the prostaglandin D2 receptor (DP/PGD2) is expressed at high levels in the scalp of men affected by male pattern baldness, the rights to setipiprant were acquired by Kythera with a view to potentially developing this drug as a novel treatment for baldness, with a previously unexploited mechanism of action. While it is too early to tell whether setipiprant will be an effective treatment for this condition, the favorable pharmacokinetics and relative lack of side effects seen in earlier clinical trials mean that fresh clinical trials for this new application can be conducted fairly quickly.".
- Setipiprant atcPrefix "none".
- Setipiprant casNumber "866460-33-5".
- Setipiprant iupacName "2-[8-fluoro-2-(naphthalene-1-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid".
- Setipiprant pubchem "49843471".
- Setipiprant thumbnail Setipiprant_structure.png?width=300.
- Setipiprant wikiPageID "47626347".
- Setipiprant wikiPageLength "4035".
- Setipiprant wikiPageOutDegree "12".
- Setipiprant wikiPageRevisionID "684675210".
- Setipiprant wikiPageWikiLink Actelion.
- Setipiprant wikiPageWikiLink Asthma.
- Setipiprant wikiPageWikiLink Category:Prostaglandins.
- Setipiprant wikiPageWikiLink Category:Receptor_antagonists.
- Setipiprant wikiPageWikiLink Clinical_trial.
- Setipiprant wikiPageWikiLink Drug.
- Setipiprant wikiPageWikiLink International_nonproprietary_name.
- Setipiprant wikiPageWikiLink Male-pattern_hair_loss.
- Setipiprant wikiPageWikiLink Prostaglandin_D2_receptor.
- Setipiprant wikiPageWikiLink Prostaglandin_DP2_receptor.
- Setipiprant wikiPageWikiLink Ramatroban.
- Setipiprant wikiPageWikiLink Receptor_antagonist.
- Setipiprant wikiPageWikiLinkText "Setipiprant".
- Setipiprant wikiPageWikiLinkText "setipiprant".
- Setipiprant atcPrefix "none".
- Setipiprant c "24".
- Setipiprant casNumber "866460".
- Setipiprant f "1".
- Setipiprant h "19".
- Setipiprant iupacName "2".
- Setipiprant molecularWeight "402.417".
- Setipiprant n "2".
- Setipiprant o "3".
- Setipiprant pubchem "49843471".
- Setipiprant routesOfAdministration "Oral".
- Setipiprant smiles "c15ccccc5cccc1CNCc2c3ncc2cc4F".
- Setipiprant wikiPageUsesTemplate Template:Drugbox.
- Setipiprant wikiPageUsesTemplate Template:Other_dermatological_preparations.
- Setipiprant wikiPageUsesTemplate Template:Pharm-stub.
- Setipiprant wikiPageUsesTemplate Template:Prostanoidergics.
- Setipiprant wikiPageUsesTemplate Template:Reflist.
- Setipiprant subject Category:Prostaglandins.
- Setipiprant subject Category:Receptor_antagonists.
- Setipiprant hypernym Drug.
- Setipiprant type ChemicalSubstance.
- Setipiprant type Drug.
- Setipiprant type ChemicalObject.
- Setipiprant type Thing.
- Setipiprant type Q8386.
- Setipiprant comment "Setipiprant (INN) (developmental code names ACT-129,968, KYTH-105) is a drug originally developed by Actelion which acts as a selective, orally available antagonist of the prostaglandin D2 receptor 2 (DP2).".
- Setipiprant label "Setipiprant".
- Setipiprant sameAs Q21098972.
- Setipiprant sameAs Q21098972.
- Setipiprant wasDerivedFrom Setipiprant?oldid=684675210.
- Setipiprant depiction Setipiprant_structure.png.
- Setipiprant isPrimaryTopicOf Setipiprant.