Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/SPEN> ?p ?o }
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- SPEN abstract "Msx2-interacting protein is a protein that in humans is encoded by the SPEN gene.This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator; this binding can modulate the activity of both liganded and nonliganded steroid receptors.".
- SPEN entrezgene "23013".
- SPEN wikiPageID "14800968".
- SPEN wikiPageLength "7370".
- SPEN wikiPageOutDegree "6".
- SPEN wikiPageRevisionID "687306710".
- SPEN wikiPageWikiLink Gene.
- SPEN wikiPageWikiLink HDAC1.
- SPEN wikiPageWikiLink Nuclear_receptor_co-repressor_2.
- SPEN wikiPageWikiLink Protein.
- SPEN wikiPageWikiLink Protein–protein_interaction.
- SPEN wikiPageWikiLink SRA1.
- SPEN wikiPageWikiLinkText "Mint".
- SPEN wikiPageWikiLinkText "SPEN".
- SPEN requireManualInspection "no".
- SPEN summaryText "This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator; this binding can modulate the activity of both liganded and nonliganded steroid receptors.".
- SPEN updateCitations "yes".
- SPEN updatePage "yes".
- SPEN updateProteinBox "yes".
- SPEN updateSummary "yes".
- SPEN wikiPageUsesTemplate Template:Cite_journal.
- SPEN wikiPageUsesTemplate Template:Gene-1-stub.
- SPEN wikiPageUsesTemplate Template:PBB.
- SPEN wikiPageUsesTemplate Template:PBB_Controls.
- SPEN wikiPageUsesTemplate Template:PBB_Further_reading.
- SPEN wikiPageUsesTemplate Template:PBB_Summary.
- SPEN wikiPageUsesTemplate Template:PDB_Gallery.
- SPEN wikiPageUsesTemplate Template:Refbegin.
- SPEN wikiPageUsesTemplate Template:Refend.
- SPEN wikiPageUsesTemplate Template:Reflist.
- SPEN hypernym Protein.
- SPEN type Biomolecule.
- SPEN type Protein.
- SPEN type Thing.
- SPEN type Q206229.
- SPEN type Q8054.
- SPEN comment "Msx2-interacting protein is a protein that in humans is encoded by the SPEN gene.This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins.".
- SPEN label "SPEN".
- SPEN sameAs Q18036655.
- SPEN sameAs SPEN.
- SPEN sameAs m.03gygbp.
- SPEN sameAs SPEN.
- SPEN sameAs Q18036655.
- SPEN wasDerivedFrom SPEN?oldid=687306710.
- SPEN isPrimaryTopicOf SPEN.