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- S-phase-promoting_factor abstract "The S-phase-promoting factor (SPF) is a CDK-cyclin complex that induces the S-phase (synthesis phase) of the cell cycle. The S-phase-promoting factor (SPF) is inhibited by Sic1 (a protein which also is a stoichiometric inhibitor of Cdk1-Clb, B-type cyclins).Sic1 releases SPF from inhibition after it is phosphorylated by G1-cyclin-CDK. The phosphorylation marking SPF for polyubiquitination by the SCF ubiquitin ligase. Then the active SPF trigger initiation of DNA synthesis.Toward the end of the G1 phase of mitosis, an SPF is phosphorylated, causing a biochemical cascade that results in the activation of DNA replication proteins and the initiation of the G1/S transition.".
- S-phase-promoting_factor wikiPageID "24170999".
- S-phase-promoting_factor wikiPageLength "1055".
- S-phase-promoting_factor wikiPageOutDegree "14".
- S-phase-promoting_factor wikiPageRevisionID "630945165".
- S-phase-promoting_factor wikiPageWikiLink Biochemical_cascade.
- S-phase-promoting_factor wikiPageWikiLink Category:Cell_cycle.
- S-phase-promoting_factor wikiPageWikiLink Category:DNA_replication.
- S-phase-promoting_factor wikiPageWikiLink Category:Enzymes.
- S-phase-promoting_factor wikiPageWikiLink Cell_cycle.
- S-phase-promoting_factor wikiPageWikiLink Cyclin-dependent_kinase_complex.
- S-phase-promoting_factor wikiPageWikiLink DNA_replication.
- S-phase-promoting_factor wikiPageWikiLink S_transition.
- S-phase-promoting_factor wikiPageWikiLink G1_phase.
- S-phase-promoting_factor wikiPageWikiLink Mitosis.
- S-phase-promoting_factor wikiPageWikiLink Phosphorylation.
- S-phase-promoting_factor wikiPageWikiLink Protein.
- S-phase-promoting_factor wikiPageWikiLink Restriction_point.
- S-phase-promoting_factor wikiPageWikiLink S_phase.
- S-phase-promoting_factor wikiPageWikiLinkText "S-phase-promoting factor".
- S-phase-promoting_factor wikiPageUsesTemplate Template:Cell_cycle_proteins.
- S-phase-promoting_factor wikiPageUsesTemplate Template:Enzyme-stub.
- S-phase-promoting_factor wikiPageUsesTemplate Template:Expert-subject.
- S-phase-promoting_factor wikiPageUsesTemplate Template:Unreferenced.
- S-phase-promoting_factor subject Category:Cell_cycle.
- S-phase-promoting_factor subject Category:DNA_replication.
- S-phase-promoting_factor subject Category:Enzymes.
- S-phase-promoting_factor comment "The S-phase-promoting factor (SPF) is a CDK-cyclin complex that induces the S-phase (synthesis phase) of the cell cycle. The S-phase-promoting factor (SPF) is inhibited by Sic1 (a protein which also is a stoichiometric inhibitor of Cdk1-Clb, B-type cyclins).Sic1 releases SPF from inhibition after it is phosphorylated by G1-cyclin-CDK. The phosphorylation marking SPF for polyubiquitination by the SCF ubiquitin ligase.".
- S-phase-promoting_factor label "S-phase-promoting factor".
- S-phase-promoting_factor sameAs Q7387121.
- S-phase-promoting_factor sameAs m.07k5g24.
- S-phase-promoting_factor sameAs Q7387121.
- S-phase-promoting_factor wasDerivedFrom S-phase-promoting_factor?oldid=630945165.
- S-phase-promoting_factor isPrimaryTopicOf S-phase-promoting_factor.