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- RprA_RNA abstract "The RprA RNA gene encodes a 106 nucleotide regulatory non-coding RNA. Translational regulation of the stationary phase sigma factor RpoS is mediated by the formation of a double-stranded RNA stem-loop structure in the upstream region of the rpoS messenger RNA, occluding the translation initiation site.Clones carrying rprA (RpoS regulator RNA A) increased the translation of RpoS. As with DsrA, RprA is predicted to form three stem-loops. Thus, at least two small RNAs, DsrA and RprA, participate in the positive regulation of RpoS translation. RprA also appears to bind to the RpoS leader. RprA is non-essential. Wasserman et al. demonstrated that this RNA is bound by the Hfq protein. Binding to Hfq alters the conformation of RprA. In the presence of Hfq the stability of RprA is influenced by the osmolarity of the cell, this is dependent on the endoribonuclease RNase E.It has been shown the RprA regulates the protein coding genes, called csgD, this protein encodes a stationary phase-induced biofilm regulator and ydaM, which encodes a diguanylate cyclase involved in activating csgD transcription. These two target genes are repressed by RprA which results in regulation of biofilm formation.".
- RprA_RNA thumbnail RF00034.jpg?width=300.
- RprA_RNA wikiPageExternalLink getdesc.cgi?id=RprA.
- RprA_RNA wikiPageID "11421458".
- RprA_RNA wikiPageLength "4914".
- RprA_RNA wikiPageOutDegree "20".
- RprA_RNA wikiPageRevisionID "618576237".
- RprA_RNA wikiPageWikiLink Bacteria.
- RprA_RNA wikiPageWikiLink Bacterial_small_RNA.
- RprA_RNA wikiPageWikiLink Biofilm.
- RprA_RNA wikiPageWikiLink Biomolecular_structure.
- RprA_RNA wikiPageWikiLink Category:Non-coding_RNA.
- RprA_RNA wikiPageWikiLink Conserved_sequence.
- RprA_RNA wikiPageWikiLink CsgD.
- RprA_RNA wikiPageWikiLink DsrA_RNA.
- RprA_RNA wikiPageWikiLink Endoribonuclease.
- RprA_RNA wikiPageWikiLink Gene.
- RprA_RNA wikiPageWikiLink Hfq_protein.
- RprA_RNA wikiPageWikiLink Non-coding_RNA.
- RprA_RNA wikiPageWikiLink Nucleotide.
- RprA_RNA wikiPageWikiLink Osmotic_concentration.
- RprA_RNA wikiPageWikiLink Repressed.
- RprA_RNA wikiPageWikiLink Ribonuclease_E.
- RprA_RNA wikiPageWikiLink RpoS.
- RprA_RNA wikiPageWikiLink Stem-loop.
- RprA_RNA wikiPageWikiLink YdaM.
- RprA_RNA wikiPageWikiLinkText "RprA RNA".
- RprA_RNA wikiPageWikiLinkText "RprA".
- RprA_RNA caption "Predicted secondary structure and sequence conservation of RprA".
- RprA_RNA id "RF00034".
- RprA_RNA name "RprA RNA".
- RprA_RNA rfam "RF00034".
- RprA_RNA rnaType Bacterial_small_RNA.
- RprA_RNA rnaType Gene.
- RprA_RNA symbol "RprA".
- RprA_RNA taxDomain Bacteria.
- RprA_RNA wikiPageUsesTemplate Template:Infobox_rfam.
- RprA_RNA wikiPageUsesTemplate Template:Molecular-cell-biology-stub.
- RprA_RNA wikiPageUsesTemplate Template:Reflist.
- RprA_RNA wikiPageUsesTemplate Template:Rfam.
- RprA_RNA wikiPageUsesTemplate Template:SO.
- RprA_RNA subject Category:Non-coding_RNA.
- RprA_RNA comment "The RprA RNA gene encodes a 106 nucleotide regulatory non-coding RNA. Translational regulation of the stationary phase sigma factor RpoS is mediated by the formation of a double-stranded RNA stem-loop structure in the upstream region of the rpoS messenger RNA, occluding the translation initiation site.Clones carrying rprA (RpoS regulator RNA A) increased the translation of RpoS. As with DsrA, RprA is predicted to form three stem-loops.".
- RprA_RNA label "RprA RNA".
- RprA_RNA sameAs Q7375545.
- RprA_RNA sameAs m.02rb_66.
- RprA_RNA sameAs Q7375545.
- RprA_RNA wasDerivedFrom RprA_RNA?oldid=618576237.
- RprA_RNA depiction RF00034.jpg.
- RprA_RNA isPrimaryTopicOf RprA_RNA.